ID   B4DW98_HUMAN            Unreviewed;       241 AA.
AC   B4DW98;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   16-JAN-2019, entry version 69.
DE   SubName: Full=cDNA FLJ54735, highly similar to SLAM family member 7 {ECO:0000313|EMBL:BAG62960.1};
GN   Name=SLAMF7 {ECO:0000313|Ensembl:ENSP00000483774};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG62960.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000483774, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000313|EMBL:BAG62960.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Synovial membrane tissue {ECO:0000313|EMBL:BAG62960.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000483774}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (SEP-2014) to UniProtKB.
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DR   EMBL; AL121985; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK301432; BAG62960.1; -; mRNA.
DR   RefSeq; NP_001269523.1; NM_001282594.1.
DR   UniGene; Hs.517265; -.
DR   SMR; B4DW98; -.
DR   PRIDE; B4DW98; -.
DR   Ensembl; ENST00000621377; ENSP00000483774; ENSG00000026751.
DR   GeneID; 57823; -.
DR   UCSC; uc010pjn.4; human.
DR   CTD; 57823; -.
DR   EuPathDB; HostDB:ENSG00000026751.16; -.
DR   HGNC; HGNC:21394; SLAMF7.
DR   OpenTargets; ENSG00000026751; -.
DR   GeneTree; ENSGT00940000153157; -.
DR   HOGENOM; HOG000013065; -.
DR   HOVERGEN; HBG079189; -.
DR   OrthoDB; 990343at2759; -.
DR   ChiTaRS; SLAMF7; human.
DR   GenomeRNAi; 57823; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000026751; Expressed in 167 organ(s), highest expression level in dorsal plus ventral thalamus.
DR   ExpressionAtlas; B4DW98; baseline and differential.
DR   GO; GO:0005783; C:endoplasmic reticulum; IDA:LIFEdb.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:B4DW98,
KW   ECO:0000213|PeptideAtlas:B4DW98};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    241       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014567690.
FT   TRANSMEM    132    156       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       24     99       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   241 AA;  27280 MW;  EE1DA0E349E46EA4 CRC64;
     MAGSPTCLTL IYILWQLTEH LSKPKVTMGL QSNKNGTCVT NLTCCMEHGE EDVIYTWKAL
     GQAANESHNG SILPISWRWG ESDMTFICVA RNPVSRNFSS PILARKLCEG DCLSPLHRRL
     CPGAADDPDS SMVLLCLLLV PLLLSLFVLG LFLWFLKRER QEEYIEEKKR VDICRETPNI
     CPHSGENTEY DTIPHTNRTI LKEDPANTVY STVEIPKKME NPHSLLTMPD TPRLFAYENV
     I
//