ID   B4DQ77_HUMAN            Unreviewed;       162 AA.
AC   B4DQ77;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   16-JAN-2019, entry version 71.
DE   SubName: Full=cDNA FLJ56671, highly similar to Integrin alpha-L {ECO:0000313|EMBL:BAG60839.1};
GN   Name=ITGAL {ECO:0000313|Ensembl:ENSP00000454342};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG60839.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000454342, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|EMBL:BAG60839.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000454342}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC002310; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC116348; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK298674; BAG60839.1; -; mRNA.
DR   UniGene; Hs.174103; -.
DR   jPOST; B4DQ77; -.
DR   MaxQB; B4DQ77; -.
DR   PeptideAtlas; B4DQ77; -.
DR   PRIDE; B4DQ77; -.
DR   Ensembl; ENST00000562857; ENSP00000454342; ENSG00000005844.
DR   UCSC; uc059ter.1; human.
DR   EuPathDB; HostDB:ENSG00000005844.17; -.
DR   HGNC; HGNC:6148; ITGAL.
DR   OpenTargets; ENSG00000005844; -.
DR   eggNOG; KOG3637; Eukaryota.
DR   eggNOG; ENOG410XPVZ; LUCA.
DR   GeneTree; ENSGT00940000161495; -.
DR   ChiTaRS; ITGAL; human.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000005844; Expressed in 210 organ(s), highest expression level in leukocyte.
DR   ExpressionAtlas; B4DQ77; baseline and differential.
DR   GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR   Gene3D; 2.130.10.130; -; 1.
DR   InterPro; IPR013519; Int_alpha_beta-p.
DR   InterPro; IPR028994; Integrin_alpha_N.
DR   PROSITE; PS51470; FG_GAP; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Integrin {ECO:0000313|EMBL:BAG60839.1};
KW   Proteomics identification {ECO:0000213|MaxQB:B4DQ77,
KW   ECO:0000213|PeptideAtlas:B4DQ77};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    162       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014085099.
FT   REPEAT       31     82       FG-GAP. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00803}.
FT   REPEAT       83    141       FG-GAP. {ECO:0000256|PROSITE-
FT                                ProRule:PRU00803}.
SQ   SEQUENCE   162 AA;  17439 MW;  C7EB098FD59CFD34 CRC64;
     MKDSCITVMA MALLSGFFFF APASSYNLDV RGARSFSPPR AGRHFGYRVL QVGNGVIVGA
     PGEGNSTGSL YQCQSGTGHC LPVTLRGSNY TSKYLGMTLA TDPTDGSILA CDPGLSRTCD
     QNTYLSGLCY LFRQNLQGPM LQGRPGFQVC CCSVFHKLQN RI
//