ID   B4DJW4_HUMAN            Unreviewed;       236 AA.
AC   B4DJW4;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   16-JAN-2019, entry version 62.
DE   SubName: Full=Group XV phospholipase A2 {ECO:0000313|Ensembl:ENSP00000457034};
DE   SubName: Full=cDNA FLJ58003, highly similar to 1-O-acylceramide synthase {ECO:0000313|EMBL:BAG58976.1};
GN   Name=PLA2G15 {ECO:0000313|Ensembl:ENSP00000457034};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG58976.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000457034, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|EMBL:BAG58976.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Thalamus {ECO:0000313|EMBL:BAG58976.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000457034}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC020978; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK296263; BAG58976.1; -; mRNA.
DR   RefSeq; XP_005255943.1; XM_005255886.3.
DR   UniGene; Hs.632199; -.
DR   SMR; B4DJW4; -.
DR   ESTHER; human-PLA2G15; PC-sterol_acyltransferase.
DR   jPOST; B4DJW4; -.
DR   MaxQB; B4DJW4; -.
DR   PRIDE; B4DJW4; -.
DR   Ensembl; ENST00000566188; ENSP00000457034; ENSG00000103066.
DR   GeneID; 23659; -.
DR   UCSC; uc010vld.3; human.
DR   CTD; 23659; -.
DR   EuPathDB; HostDB:ENSG00000103066.12; -.
DR   HGNC; HGNC:17163; PLA2G15.
DR   OpenTargets; ENSG00000103066; -.
DR   eggNOG; KOG2369; Eukaryota.
DR   eggNOG; ENOG410Y9CF; LUCA.
DR   GeneTree; ENSGT00940000157499; -.
DR   HOVERGEN; HBG102668; -.
DR   OrthoDB; 828056at2759; -.
DR   ChiTaRS; PLA2G15; human.
DR   GenomeRNAi; 23659; -.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000103066; Expressed in 166 organ(s), highest expression level in heart left ventricle.
DR   ExpressionAtlas; B4DJW4; baseline and differential.
DR   GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR   GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.1820; -; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR003386; LACT/PDAT_acylTrfase.
DR   Pfam; PF02450; LCAT; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:B4DJW4,
KW   ECO:0000213|PeptideAtlas:B4DJW4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     33       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        34    236       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014085103.
SQ   SEQUENCE   236 AA;  25847 MW;  A8C6B0E345C76020 CRC64;
     MGLHLRPYRV GLLPDGLLFL LLLLMLLADP ALPAGRHPPV VLVPGDLGNQ LEAKLDKPTV
     VHYLCSKKTE SYFTIWLNLE LLLPVIIDCW IDNIRLVYNK TSRATQFPDG VDVRVPGFGK
     TFSLEFLDPS KSSVGSYFHT MVESLVGWGY TRGEDVRGAP YDWRRAPTAA AGLEGQVYPG
     LRVTGCALGG RGQDPARPGF RRQQPDPSHR APEDPGAAAV SCLHQLAAAL QLHMVT
//