ID   B4DJK6_HUMAN            Unreviewed;       101 AA.
AC   B4DJK6;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   16-JAN-2019, entry version 72.
DE   SubName: Full=N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase {ECO:0000313|Ensembl:ENSP00000464424};
DE   SubName: Full=cDNA FLJ50779, moderately similar to N-acetylglucosaminyl-phosphatidylinositolde-N-acetylase {ECO:0000313|EMBL:BAG58868.1};
GN   Name=PIGL {ECO:0000313|Ensembl:ENSP00000464424};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG58868.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000464424, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|EMBL:BAG58868.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Thalamus {ECO:0000313|EMBL:BAG58868.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000464424}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2012) to UniProtKB.
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DR   EMBL; AC005971; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK296120; BAG58868.1; -; mRNA.
DR   UniGene; Hs.499793; -.
DR   UniGene; Hs.625050; -.
DR   jPOST; B4DJK6; -.
DR   MaxQB; B4DJK6; -.
DR   Ensembl; ENST00000585034; ENSP00000464424; ENSG00000108474.
DR   UCSC; uc060brk.1; human.
DR   EuPathDB; HostDB:ENSG00000108474.16; -.
DR   HGNC; HGNC:8966; PIGL.
DR   OpenTargets; ENSG00000108474; -.
DR   eggNOG; KOG3332; Eukaryota.
DR   eggNOG; COG2120; LUCA.
DR   GeneTree; ENSGT00390000018434; -.
DR   HOVERGEN; HBG093103; -.
DR   ChiTaRS; PIGL; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000108474; Expressed in 186 organ(s), highest expression level in corpus callosum.
DR   ExpressionAtlas; B4DJK6; baseline and differential.
DR   GO; GO:0000225; F:N-acetylglucosaminylphosphatidylinositol deacetylase activity; IEA:InterPro.
DR   GO; GO:0006506; P:GPI anchor biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.50.10320; -; 1.
DR   InterPro; IPR003737; GlcNAc_PI_deacetylase-related.
DR   InterPro; IPR039516; GPI12.
DR   InterPro; IPR024078; LmbE-like_dom_sf.
DR   PANTHER; PTHR12993; PTHR12993; 1.
DR   PANTHER; PTHR12993:SF11; PTHR12993:SF11; 1.
DR   Pfam; PF02585; PIG-L; 1.
DR   SUPFAM; SSF102588; SSF102588; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:B4DJK6,
KW   ECO:0000213|PeptideAtlas:B4DJK6};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    101       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014085100.
SQ   SEQUENCE   101 AA;  11301 MW;  9E002BA7475448BE CRC64;
     MEAMWLLCVA LAVLAWGFLW VWDSSERMKS REQGGRLGAE SRTLLVIAHP DDEAMFFAPT
     VLGLARLRHW VYLLCFSAGI SQMTQACSGT QSTWPESSFS T
//