ID   B4DJG1_HUMAN            Unreviewed;       136 AA.
AC   B4DJG1;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   16-JAN-2019, entry version 75.
DE   SubName: Full=HLA class II histocompatibility antigen, DQ beta 1 chain {ECO:0000313|Ensembl:ENSP00000435178};
DE   SubName: Full=cDNA FLJ53582, highly similar to HLA class II histocompatibility antigen, DQ(1)beta chain {ECO:0000313|EMBL:BAG58823.1};
GN   Name=HLA-DQB1 {ECO:0000313|Ensembl:ENSP00000435178};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG58823.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000435178, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14574404; DOI=10.1038/nature02055;
RA   Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA   Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA   Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA   Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA   Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA   Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA   Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA   Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA   Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA   Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA   Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA   Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA   Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA   Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA   Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA   Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA   Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA   McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA   Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA   Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA   Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA   Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA   Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA   Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA   Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA   Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA   Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT   "The DNA sequence and analysis of human chromosome 6.";
RL   Nature 425:805-811(2003).
RN   [2] {ECO:0000313|EMBL:BAG58823.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Thalamus {ECO:0000313|EMBL:BAG58823.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000435178}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; BX927168; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK296060; BAG58823.1; -; mRNA.
DR   UniGene; Hs.409934; -.
DR   UniGene; Hs.534322; -.
DR   EPD; B4DJG1; -.
DR   jPOST; B4DJG1; -.
DR   MaxQB; B4DJG1; -.
DR   PRIDE; B4DJG1; -.
DR   Ensembl; ENST00000473366; ENSP00000435178; ENSG00000225824.
DR   UCSC; uc063wye.1; human.
DR   HGNC; HGNC:4944; HLA-DQB1.
DR   HOVERGEN; HBG012730; -.
DR   ChiTaRS; HLA-DQB1; human.
DR   Proteomes; UP000005640; Chromosome 6.
DR   GO; GO:0042613; C:MHC class II protein complex; IEA:InterPro.
DR   GO; GO:0019882; P:antigen processing and presentation; IEA:InterPro.
DR   GO; GO:0006955; P:immune response; IEA:InterPro.
DR   Gene3D; 3.10.320.10; -; 1.
DR   InterPro; IPR011162; MHC_I/II-like_Ag-recog.
DR   InterPro; IPR014745; MHC_II_a/b_N.
DR   InterPro; IPR000353; MHC_II_b_N.
DR   Pfam; PF00969; MHC_II_beta; 1.
DR   ProDom; PD000328; MHC_II_b_N; 1.
DR   SMART; SM00921; MHC_II_beta; 1.
DR   SUPFAM; SSF54452; SSF54452; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:B4DJG1,
KW   ECO:0000213|PeptideAtlas:B4DJG1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     32       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        33    136       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014567680.
FT   DOMAIN       45    119       MHC_II_beta. {ECO:0000259|SMART:SM00921}.
SQ   SEQUENCE   136 AA;  15679 MW;  BA1C9E4CFB258A89 CRC64;
     MSWKKALRIP GGLRAATVTL MLSMLSTPVA EGRDSPEDFV YQFKGMCYFT NGTERVRLVS
     RSIYNREEIV RFDSDVGEFR AVTLLGLPAA EYWNSQKDIL ERKRAAVDRV CRHNYQLELR
     TTLQRRGMVT GPSRSW
//