ID   B4DIB9_HUMAN            Unreviewed;       245 AA.
AC   B4DIB9;
DT   23-SEP-2008, integrated into UniProtKB/TrEMBL.
DT   23-SEP-2008, sequence version 1.
DT   16-JAN-2019, entry version 59.
DE   SubName: Full=cDNA FLJ55161, highly similar to Tectonic-1 {ECO:0000313|EMBL:BAG58431.1};
GN   Name=TCTN1 {ECO:0000313|Ensembl:ENSP00000473789};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG58431.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000473789, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16541075; DOI=10.1038/nature04569;
RG   Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team;
RA   Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y.,
RA   Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C.,
RA   Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M.,
RA   Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA   Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D.,
RA   Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z.,
RA   Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H.,
RA   Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H.,
RA   Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V.,
RA   Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J.,
RA   Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A.,
RA   Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M.,
RA   Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E.,
RA   Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K.,
RA   Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D.,
RA   Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M.,
RA   Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R.,
RA   Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J.,
RA   Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C.,
RA   Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M.,
RA   Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M.,
RA   Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P.,
RA   Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L.,
RA   Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E.,
RA   Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C.,
RA   Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F.,
RA   Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M.,
RA   Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S.,
RA   Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J.,
RA   Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A.,
RA   Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M.,
RA   Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I.,
RA   Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A.,
RA   Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D.,
RA   Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I.,
RA   Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T.,
RA   Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S.,
RA   Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D.,
RA   Kucherlapati R., Weinstock G., Gibbs R.A., null.;
RT   "The finished DNA sequence of human chromosome 12.";
RL   Nature 440:346-351(2006).
RN   [2] {ECO:0000313|EMBL:BAG58431.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Hippocampus {ECO:0000313|EMBL:BAG58431.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000473789}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2013) to UniProtKB.
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DR   EMBL; AC002350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC144522; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK295514; BAG58431.1; -; mRNA.
DR   RefSeq; NP_001076006.1; NM_001082537.2.
DR   RefSeq; NP_001076007.1; NM_001082538.2.
DR   RefSeq; NP_001167446.1; NM_001173975.2.
DR   RefSeq; NP_001167447.1; NM_001173976.1.
DR   RefSeq; NP_001306610.1; NM_001319681.1.
DR   RefSeq; NP_001306611.1; NM_001319682.1.
DR   RefSeq; NP_078825.2; NM_024549.5.
DR   UniGene; Hs.211511; -.
DR   PeptideAtlas; B4DIB9; -.
DR   Ensembl; ENST00000550703; ENSP00000473789; ENSG00000204852.
DR   GeneID; 79600; -.
DR   KEGG; hsa:79600; -.
DR   UCSC; uc010syb.3; human.
DR   CTD; 79600; -.
DR   EuPathDB; HostDB:ENSG00000204852.15; -.
DR   HGNC; HGNC:26113; TCTN1.
DR   OpenTargets; ENSG00000204852; -.
DR   eggNOG; ENOG410IFF2; Eukaryota.
DR   eggNOG; ENOG411028N; LUCA.
DR   GeneTree; ENSGT00570000079101; -.
DR   HOVERGEN; HBG082302; -.
DR   KO; K19382; -.
DR   OrthoDB; 446525at2759; -.
DR   GenomeRNAi; 79600; -.
DR   Proteomes; UP000005640; Chromosome 12.
DR   Bgee; ENSG00000204852; Expressed in 172 organ(s), highest expression level in right uterine tube.
DR   ExpressionAtlas; B4DIB9; baseline and differential.
DR   InterPro; IPR011677; DUF1619.
DR   InterPro; IPR040354; Tectonic.
DR   PANTHER; PTHR14611; PTHR14611; 1.
DR   Pfam; PF07773; DUF1619; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:B4DIB9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    245       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014085093.
FT   DOMAIN       78    209       DUF1619. {ECO:0000259|Pfam:PF07773}.
SQ   SEQUENCE   245 AA;  26395 MW;  7E7D987FFB32F69F CRC64;
     MRPRGLPPLL VVLLGCWASV SAQTDATPAV TTEGLNSTEA ALATFGTFPS TRPPGTPRAP
     GPSSGPRPTP VTDVAVLCVC DLSPAQCDIN CCCDPDCSSV DFSVFSACSV PVVTGDSQFC
     SQKAVIYSLN FTANPPQRVF ELVDQINPSI FCIHITNYKP ALSFINPEVP DENNFDTLMK
     TSDGFTLNAE SYVSFTTKLD IPTAAKYEVS LNLIDSFHPI TNIFPCKLIF KVTRKTGFLE
     TELIL
//