ID   B1AP13_HUMAN            Unreviewed;       444 AA.
AC   B1AP13;
DT   08-APR-2008, integrated into UniProtKB/TrEMBL.
DT   08-APR-2008, sequence version 1.
DT   16-JAN-2019, entry version 93.
DE   SubName: Full=Complement decay-accelerating factor {ECO:0000313|Ensembl:ENSP00000356030};
GN   Name=CD55 {ECO:0000313|Ensembl:ENSP00000356030};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000356030, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000356030, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S., Hart E., Haugen E., Heath P.D., Holmes S.,
RA   Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J.,
RA   James R., Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K.,
RA   Kibukawa M., Kimberley A.M., King A., Knights A.J., Lad H., Laird G.,
RA   Lawlor S., Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J.,
RA   Lush M.J., Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L.,
RA   Matthews N.S., McLaren S., Milne S., Mistry S., Moore M.J.,
RA   Nickerson T., O'Dell C.N., Oliver K., Palmeiri A., Palmer S.A.,
RA   Parker A., Patel D., Pearce A.V., Peck A.I., Pelan S., Phelps K.,
RA   Phillimore B.J., Plumb R., Rajan J., Raymond C., Rouse G.,
RA   Saenphimmachak C., Sehra H.K., Sheridan E., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M., Steward C., Subramanian S., Sycamore N.,
RA   Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M., White S.,
RA   Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H., Wilming L.,
RA   Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E., Durbin R.,
RA   Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G., Ross M.T.,
RA   Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R., Banerjee R.,
RA   Bryant S.P., Burford D.C., Burrill W.D., Clegg S.M., Dhami P.,
RA   Dovey O., Faulkner L.M., Gribble S.M., Langford C.F., Pandian R.D.,
RA   Porter K.M., Prigmore E.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000356030}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00302}.
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DR   EMBL; AL391597; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL596218; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001287831.1; NM_001300902.1.
DR   UniGene; Hs.126517; -.
DR   UniGene; Hs.609950; -.
DR   ProteinModelPortal; B1AP13; -.
DR   SMR; B1AP13; -.
DR   EPD; B1AP13; -.
DR   jPOST; B1AP13; -.
DR   MaxQB; B1AP13; -.
DR   PeptideAtlas; B1AP13; -.
DR   PRIDE; B1AP13; -.
DR   Ensembl; ENST00000367063; ENSP00000356030; ENSG00000196352.
DR   GeneID; 1604; -.
DR   UCSC; uc031vma.2; human.
DR   CTD; 1604; -.
DR   EuPathDB; HostDB:ENSG00000196352.14; -.
DR   HGNC; HGNC:2665; CD55.
DR   OpenTargets; ENSG00000196352; -.
DR   eggNOG; ENOG410IEGQ; Eukaryota.
DR   eggNOG; ENOG410XPJ1; LUCA.
DR   GeneTree; ENSGT00940000162307; -.
DR   HOGENOM; HOG000237360; -.
DR   HOVERGEN; HBG001406; -.
DR   OMA; GYRQSIT; -.
DR   OrthoDB; 1101732at2759; -.
DR   PhylomeDB; B1AP13; -.
DR   ChiTaRS; CD55; human.
DR   GenomeRNAi; 1604; -.
DR   Proteomes; UP000005640; Chromosome 1.
DR   Bgee; ENSG00000196352; Expressed in 228 organ(s), highest expression level in nasal cavity epithelium.
DR   ExpressionAtlas; B1AP13; baseline and differential.
DR   CDD; cd00033; CCP; 4.
DR   InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR   InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR   Pfam; PF00084; Sushi; 4.
DR   SMART; SM00032; CCP; 4.
DR   SUPFAM; SSF57535; SSF57535; 4.
DR   PROSITE; PS50923; SUSHI; 4.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00887447};
KW   Proteomics identification {ECO:0000213|EPD:B1AP13,
KW   ECO:0000213|MaxQB:B1AP13, ECO:0000213|PeptideAtlas:B1AP13};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Sushi {ECO:0000256|PROSITE-ProRule:PRU00302}.
FT   SIGNAL        1     34       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        35    444       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002761429.
FT   DOMAIN       34     94       Sushi. {ECO:0000259|PROSITE:PS50923}.
FT   DOMAIN       96    160       Sushi. {ECO:0000259|PROSITE:PS50923}.
FT   DOMAIN      161    222       Sushi. {ECO:0000259|PROSITE:PS50923}.
FT   DOMAIN      223    285       Sushi. {ECO:0000259|PROSITE:PS50923}.
SQ   SEQUENCE   444 AA;  49338 MW;  38B7D12413F52A23 CRC64;
     MTVARPSVPA ALPLLGELPR LLLLVLLCLP AVWGDCGLPP DVPNAQPALE GRTSFPEDTV
     ITYKCEESFV KIPGEKDSVI CLKGSQWSDI EEFCNRSCEV PTRLNSASLK QPYITQNYFP
     VGTVVEYECR PGYRREPSLS PKLTCLQNLK WSTAVEFCKK KSCPNPGEIR NGQIDVPGGI
     LFGATISFSC NTGYKLFGST SSFCLISGSS VQWSDPLPEC REIYCPAPPQ IDNGIIQGER
     DHYGYRQSVT YACNKGFTMI GEHSIYCTVN NDEGEWSGPP PECRGKSLTS KVPPTVQKPT
     TVNVPTTEVS PTSQKTTTKT TTPNAQATRS TPVSRTTKHF HETTPNKGSG TTSGTTRLLS
     GSRPVTQAGM RWCDRSSLQS RTPGFKRSFH FSLPSSWYYR CVPRHPAKFL KFIFCRDRIF
     LCCPGWFQTP GRKRFFRPPK TLRL
//