ID   A8MZH0_HUMAN            Unreviewed;       454 AA.
AC   A8MZH0;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   29-OCT-2014, sequence version 2.
DT   16-JAN-2019, entry version 71.
DE   SubName: Full=Leukocyte immunoglobulin-like receptor subfamily A member 2 {ECO:0000313|Ensembl:ENSP00000375617};
GN   Name=LILRA2 {ECO:0000313|Ensembl:ENSP00000375617};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000375617, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000375617, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000375617}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AC245036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001277199.1; NM_001290270.1.
DR   RefSeq; XP_011524689.1; XM_011526387.1.
DR   UniGene; Hs.655593; -.
DR   UniGene; Hs.739156; -.
DR   ProteinModelPortal; A8MZH0; -.
DR   jPOST; A8MZH0; -.
DR   PRIDE; A8MZH0; -.
DR   Ensembl; ENST00000391737; ENSP00000375617; ENSG00000239998.
DR   GeneID; 11027; -.
DR   UCSC; uc010ero.5; human.
DR   CTD; 11027; -.
DR   EuPathDB; HostDB:ENSG00000239998.5; -.
DR   HGNC; HGNC:6603; LILRA2.
DR   OpenTargets; ENSG00000239998; -.
DR   GeneTree; ENSGT00940000153160; -.
DR   HOGENOM; HOG000234395; -.
DR   HOVERGEN; HBG074353; -.
DR   OrthoDB; 1000446at2759; -.
DR   ChiTaRS; LILRA2; human.
DR   GenomeRNAi; 11027; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000239998; Expressed in 165 organ(s), highest expression level in blood.
DR   ExpressionAtlas; A8MZH0; baseline and differential.
DR   Gene3D; 2.60.40.10; -; 4.
DR   InterPro; IPR016332; A1B_glyco/leuk_Ig-like_rcpt.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 1.
DR   Pfam; PF13895; Ig_2; 1.
DR   PIRSF; PIRSF001979; Alpha_1B_glycoprot_prd; 2.
DR   SMART; SM00409; IG; 4.
DR   SMART; SM00408; IGc2; 3.
DR   SUPFAM; SSF48726; SSF48726; 4.
DR   PROSITE; PS50835; IG_LIKE; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR001979-1};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Proteomics identification {ECO:0000213|MaxQB:A8MZH0,
KW   ECO:0000213|PeptideAtlas:A8MZH0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    454       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002726090.
FT   DOMAIN       15    101       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      212    301       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DISULFID     37     85       {ECO:0000256|PIRSR:PIRSR001979-1}.
FT   DISULFID    131    183       {ECO:0000256|PIRSR:PIRSR001979-1}.
SQ   SEQUENCE   454 AA;  49956 MW;  0CB0FF8B3007821B CRC64;
     MTPILTVLIC LGHLPKPTLW AEPGSVIIQG SPVTLRCQGS LQAEEYHLYR ENKSASWVRR
     IQEPGKNGQF PIPSITWEHA GRYHCQYYSH NHSSEYSDPL ELVVTGAYSK PTLSALPSPV
     VTSGGNVTLQ CVSQVAFDGF ILCKEGEDEH PQRLNSHSHA RGWSWAIFSV GPVSPSRRWS
     YRCYAYDSNS PYVWSLPSDL LELLVPGVSK KPSLSVQPGP MVAPGESLTL QCVSDVGYDR
     FVLYKEGERD FLQRPGWQPQ AGLSQANFTL GPVSPSHGGQ YRCYSAHNLS SEWSAPSDPL
     DILITGQFYD RPSLSVQPVP TVAPGKNVTL LCQSRGQFHT FLLTKEGAGH PPLHLRSEHQ
     AQQNQAEFRM GPVTSAHVGT YRCYSSLSSN PYLLSLPSDP LELVVSASLG QHPQDYTVEN
     LIRMGVAGLV LVVLGILLFE AQHSQRSLQD AAGR
//