ID   BTNLA_HUMAN             Reviewed;         291 AA.
AC   A8MVZ5;
DT   16-MAY-2012, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2012, sequence version 2.
DT   16-JAN-2019, entry version 62.
DE   RecName: Full=Butyrophilin-like protein 10;
DE   Flags: Precursor;
GN   Name=BTNL10;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,
RA   Dunham A., Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A.,
RA   Jones M.C., Gillson C., Searle S., Zhou Y., Kokocinski F.,
RA   McDonald L., Evans R., Phillips K., Atkinson A., Cooper R., Jones C.,
RA   Hall R.E., Andrews T.D., Lloyd C., Ainscough R., Almeida J.P.,
RA   Ambrose K.D., Anderson F., Andrew R.W., Ashwell R.I.S., Aubin K.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Beasley H., Bethel G.,
RA   Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J., Buckley D.,
RA   Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y., Clarke G.,
RA   Clee C., Cobley V., Collier R.E., Corby N., Coville G.J., Davies J.,
RA   Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R.,
RA   Hammond S., Harrison E.S.I., Hart E., Haugen E., Heath P.D.,
RA   Holmes S., Holt K., Howden P.J., Hunt A.R., Hunt S.E., Hunter G.,
RA   Isherwood J., James R., Johnson C., Johnson D., Joy A., Kay M.,
RA   Kershaw J.K., Kibukawa M., Kimberley A.M., King A., Knights A.J.,
RA   Lad H., Laird G., Lawlor S., Leongamornlert D.A., Lloyd D.M.,
RA   Loveland J., Lovell J., Lush M.J., Lyne R., Martin S.,
RA   Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W., McLaren S.,
RA   Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA   Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA   Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA   Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA   Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C.,
RA   Subramanian S., Sycamore N., Tracey A., Tromans A., Van Helmond Z.,
RA   Wall M., Wallis J.M., White S., Whitehead S.L., Wilkinson J.E.,
RA   Willey D.L., Williams H., Wilming L., Wray P.W., Wu Z., Coulson A.,
RA   Vaudin M., Sulston J.E., Durbin R.M., Hubbard T., Wooster R.,
RA   Dunham I., Carter N.P., McVean G., Ross M.T., Harrow J., Olson M.V.,
RA   Beck S., Rogers J., Bentley D.R.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass type I
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the immunoglobulin superfamily. BTN/MOG
CC       family. {ECO:0000305}.
CC   -!- CAUTION: Product of a dubious gene prediction. {ECO:0000305}.
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DR   EMBL; AL139288; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   UniGene; Hs.730208; -.
DR   ProteinModelPortal; A8MVZ5; -.
DR   SMR; A8MVZ5; -.
DR   BioMuta; HGNC:42540; -.
DR   PRIDE; A8MVZ5; -.
DR   ProteomicsDB; 2214; -.
DR   GeneCards; BTNL10; -.
DR   HGNC; HGNC:42540; BTNL10.
DR   neXtProt; NX_A8MVZ5; -.
DR   HOGENOM; HOG000231211; -.
DR   HOVERGEN; HBG078070; -.
DR   InParanoid; A8MVZ5; -.
DR   Proteomes; UP000005640; Unplaced.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005102; F:signaling receptor binding; IBA:GO_Central.
DR   GO; GO:0050776; P:regulation of immune response; IBA:GO_Central.
DR   GO; GO:0050852; P:T cell receptor signaling pathway; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   5: Uncertain;
KW   Complete proteome; Disulfide bond; Glycoprotein;
KW   Immunoglobulin domain; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL        1     26       {ECO:0000255}.
FT   CHAIN        27    291       Butyrophilin-like protein 10.
FT                                /FTId=PRO_0000417553.
FT   TOPO_DOM     27    254       Extracellular. {ECO:0000255}.
FT   TRANSMEM    255    275       Helical. {ECO:0000255}.
FT   TOPO_DOM    276    291       Cytoplasmic. {ECO:0000255}.
FT   DOMAIN       27    146       Ig-like V-type.
FT   CARBOHYD     59     59       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   DISULFID     54    128       {ECO:0000255|PROSITE-ProRule:PRU00114}.
SQ   SEQUENCE   291 AA;  32612 MW;  FFF69D3BE859F163 CRC64;
     MAVTCDPEAF LSICFVTLVF LQLPLASIWK ADFDVTGPHA PILAMAGGHV ELQCQLFPNI
     SAEDMELRWY RCQPSLAVHM HERGMDMDGE QKWQYRGRTT FMSDHVARGK AMVRSHRVTT
     FDNRTYCCRF KDGVKFGEAT VQVQVAGLGR EPRIQVTDQQ DGVRAECTSA GCFPKSWVER
     RDFRGQARPA VTNLSASATT RLWAVASSLT LWDRAVEGLS CSISSPLLPE RRKVAESHLP
     ATFSRSSQFT AWKAALPLIL VAMGLVIAGG ICIFWKRQRE KNKASLEEER E
//