ID   HIDE1_HUMAN             Reviewed;         230 AA.
AC   A8MVS5; B2RXI3;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 2.
DT   13-FEB-2019, entry version 86.
DE   RecName: Full=Protein HIDE1;
DE   Flags: Precursor;
GN   Name=HIDE1; Synonyms=C19orf38;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA   Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA   Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA   Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA   Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA   Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA   Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA   Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA
RT   project: the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane
CC       protein.
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DR   EMBL; AC007565; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471106; EAW84154.1; -; Genomic_DNA.
DR   EMBL; BC157863; AAI57864.1; -; mRNA.
DR   CCDS; CCDS45970.1; -.
DR   RefSeq; NP_001129954.1; NM_001136482.1.
DR   RefSeq; XP_005259903.1; XM_005259846.4.
DR   RefSeq; XP_005259904.1; XM_005259847.4.
DR   UniGene; Hs.440535; -.
DR   ProteinModelPortal; A8MVS5; -.
DR   BioGrid; 129122; 80.
DR   IntAct; A8MVS5; 2.
DR   iPTMnet; A8MVS5; -.
DR   PhosphoSitePlus; A8MVS5; -.
DR   BioMuta; C19orf38; -.
DR   jPOST; A8MVS5; -.
DR   MaxQB; A8MVS5; -.
DR   PaxDb; A8MVS5; -.
DR   PRIDE; A8MVS5; -.
DR   ProteomicsDB; 2201; -.
DR   Ensembl; ENST00000397820; ENSP00000380920; ENSG00000214212.
DR   Ensembl; ENST00000592854; ENSP00000468568; ENSG00000214212.
DR   GeneID; 255809; -.
DR   KEGG; hsa:255809; -.
DR   UCSC; uc010dxm.2; human.
DR   CTD; 255809; -.
DR   EuPathDB; HostDB:ENSG00000214212.8; -.
DR   GeneCards; C19orf38; -.
DR   HGNC; HGNC:34073; C19orf38.
DR   HPA; HPA012150; -.
DR   HPA; HPA055027; -.
DR   neXtProt; NX_A8MVS5; -.
DR   OpenTargets; ENSG00000214212; -.
DR   PharmGKB; PA162378624; -.
DR   eggNOG; ENOG410IJQU; Eukaryota.
DR   eggNOG; ENOG4111B01; LUCA.
DR   GeneTree; ENSGT00390000008862; -.
DR   HOGENOM; HOG000112895; -.
DR   HOVERGEN; HBG107977; -.
DR   InParanoid; A8MVS5; -.
DR   OMA; CWAQVNF; -.
DR   OrthoDB; 1400769at2759; -.
DR   PhylomeDB; A8MVS5; -.
DR   GenomeRNAi; 255809; -.
DR   PRO; PR:A8MVS5; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000214212; Expressed in 91 organ(s), highest expression level in blood.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR040438; HIDE1.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR36859; PTHR36859; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome; Glycoprotein; Membrane; Reference proteome; Signal;
KW   Transmembrane; Transmembrane helix.
FT   SIGNAL        1     19       {ECO:0000255}.
FT   CHAIN        20    230       Protein HIDE1.
FT                                /FTId=PRO_0000341217.
FT   TOPO_DOM     20    117       Extracellular. {ECO:0000255}.
FT   TRANSMEM    118    138       Helical. {ECO:0000255}.
FT   TOPO_DOM    139    230       Cytoplasmic. {ECO:0000255}.
FT   CARBOHYD     48     48       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD     97     97       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
SQ   SEQUENCE   230 AA;  24753 MW;  F11C80C478E04DC0 CRC64;
     MPWTILLFAA GSLAIPAPSI RLVPPYPSSQ EDPIHIACMA PGNFPGANFT LYRGGQVVQL
     LQAPTDQRGV TFNLSGGSSK APGGPFHCQY GVLGELNQSQ LSDLSEPVNV SFPVPTWILV
     LSLSLAGALF LLAGLVAVAL VVRKVKLRNL QKKRDRESCW AQINFDSTDM SFDNSLFTVS
     AKTMPEEDPA TLDDHSGTTA TPSNSRTRKR PTSTSSSPET PEFSTFRACQ
//