ID   A6PVD9_HUMAN            Unreviewed;       136 AA.
AC   A6PVD9;
DT   21-AUG-2007, integrated into UniProtKB/TrEMBL.
DT   21-AUG-2007, sequence version 1.
DT   05-DEC-2018, entry version 73.
DE   SubName: Full=Collagen alpha-1(XXI) chain {ECO:0000313|Ensembl:ENSP00000359853};
DE   Flags: Fragment;
GN   Name=COL21A1 {ECO:0000313|Ensembl:ENSP00000359853};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000359853, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000359853, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14574404; DOI=10.1038/nature02055;
RA   Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA   Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA   Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA   Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA   Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA   Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA   Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA   Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA   Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA   Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA   Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA   Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA   Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA   Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA   Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA   Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA   Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA   McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA   Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA   Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA   Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA   Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA   Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA   Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA   Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA   Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA   Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT   "The DNA sequence and analysis of human chromosome 6.";
RL   Nature 425:805-811(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000359853}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AL031779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL031782; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL034452; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL450430; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL513530; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL590675; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A6PVD9; -.
DR   SMR; A6PVD9; -.
DR   PeptideAtlas; A6PVD9; -.
DR   PRIDE; A6PVD9; -.
DR   Ensembl; ENST00000370817; ENSP00000359853; ENSG00000124749.
DR   UCSC; uc063pei.1; human.
DR   EuPathDB; HostDB:ENSG00000124749.16; -.
DR   HGNC; HGNC:17025; COL21A1.
DR   OpenTargets; ENSG00000124749; -.
DR   eggNOG; ENOG410IS78; Eukaryota.
DR   eggNOG; ENOG41100RI; LUCA.
DR   GeneTree; ENSGT00940000162318; -.
DR   HOGENOM; HOG000085653; -.
DR   Proteomes; UP000005640; Chromosome 6.
DR   Bgee; ENSG00000124749; Expressed in 192 organ(s), highest expression level in metanephros.
DR   ExpressionAtlas; A6PVD9; baseline and differential.
DR   Gene3D; 3.40.50.410; -; 1.
DR   InterPro; IPR002035; VWF_A.
DR   InterPro; IPR036465; vWFA_dom_sf.
DR   Pfam; PF00092; VWA; 1.
DR   SUPFAM; SSF53300; SSF53300; 1.
DR   PROSITE; PS50234; VWFA; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A6PVD9,
KW   ECO:0000213|PeptideAtlas:A6PVD9};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    136       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002700940.
FT   DOMAIN       37    136       VWFA. {ECO:0000259|PROSITE:PS50234}.
FT   NON_TER     136    136       {ECO:0000313|Ensembl:ENSP00000359853}.
SQ   SEQUENCE   136 AA;  15047 MW;  269C12539918E5E1 CRC64;
     MAHYITFLCM VLVLLLQNSV LAEDGEVRSS CRTAPTDLVF ILDGSYSVGP ENFEIVKKWL
     VNITKNFDIG PKFIQVGVVQ YSDYPVLEIP LGSYDSGEHL TAAVESILYL GGNTKTGKAI
     QFALDYLFAK SSRFLT
//