ID   A6NP03_HUMAN            Unreviewed;       280 AA.
AC   A6NP03;
DT   24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   28-JUN-2011, sequence version 2.
DT   13-FEB-2019, entry version 70.
DE   SubName: Full=UDP-glucose:glycoprotein glucosyltransferase 2 {ECO:0000313|Ensembl:ENSP00000365902};
GN   Name=UGGT2 {ECO:0000313|Ensembl:ENSP00000365902};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000365902, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000365902, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057823; DOI=10.1038/nature02379;
RA   Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L.,
RA   Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E.,
RA   Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E.,
RA   Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.,
RA   Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R.,
RA   Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S.,
RA   Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P.,
RA   Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M.,
RA   Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J.,
RA   Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E.,
RA   Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L.,
RA   Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J.,
RA   Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S.,
RA   Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J.,
RA   Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M.,
RA   King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A.,
RA   Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S.,
RA   Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S.,
RA   Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I.,
RA   Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S.,
RA   Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A.,
RA   Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L.,
RA   Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.,
RA   Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.;
RT   "The DNA sequence and analysis of human chromosome 13.";
RL   Nature 428:522-528(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000365902}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
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DR   EMBL; AL136104; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL158192; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL162500; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL607038; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A6NP03; -.
DR   jPOST; A6NP03; -.
DR   MaxQB; A6NP03; -.
DR   PeptideAtlas; A6NP03; -.
DR   PRIDE; A6NP03; -.
DR   Ensembl; ENST00000376712; ENSP00000365902; ENSG00000102595.
DR   UCSC; uc058xus.1; human.
DR   EuPathDB; HostDB:ENSG00000102595.18; -.
DR   HGNC; HGNC:15664; UGGT2.
DR   OpenTargets; ENSG00000102595; -.
DR   eggNOG; KOG1879; Eukaryota.
DR   eggNOG; ENOG410XRK6; LUCA.
DR   GeneTree; ENSGT00390000004600; -.
DR   HOGENOM; HOG000293330; -.
DR   HOVERGEN; HBG055546; -.
DR   ChiTaRS; UGGT2; human.
DR   Proteomes; UP000005640; Chromosome 13.
DR   Bgee; ENSG00000102595; Expressed in 207 organ(s), highest expression level in intestine.
DR   ExpressionAtlas; A6NP03; baseline and differential.
DR   GO; GO:0003980; F:UDP-glucose:glycoprotein glucosyltransferase activity; IEA:InterPro.
DR   GO; GO:0006486; P:protein glycosylation; IEA:InterPro.
DR   InterPro; IPR009448; UDP-g_GGtrans.
DR   InterPro; IPR040693; UGGT_TRXL_1.
DR   PANTHER; PTHR11226; PTHR11226; 1.
DR   Pfam; PF18400; Thioredoxin_12; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A6NP03,
KW   ECO:0000213|PeptideAtlas:A6NP03};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28    280       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002700585.
FT   DOMAIN       45    226       Thioredoxin_12.
FT                                {ECO:0000259|Pfam:PF18400}.
SQ   SEQUENCE   280 AA;  31714 MW;  BA4609B126D4F730 CRC64;
     MAPAKATNVV RLLLGSTALW LSQLGSGTVA ASKSVTAHLA AKWPETPLLL EASEFMAEES
     NEKFWQFLET VQELAIYKQT ESDYSYYNLI LKKAGQFLDN LHINLLKFAF SIRAYSPAIQ
     MFQQIAADEP PPDGCNAFVV IHKKHTCKIN EIKKLLKKAA SRTRPYLFKG DHKFPTNKEN
     LPVVILYAEM GTRTFSAFHK VLSEKAQNEE ILYVLRHYIQ KPSSRKMYLS GYGVELAIKS
     TEYKALDDTQ VKTVTNTTVE DETETNEVQG FLFGKLKLVY
//