ID   A6NL85_HUMAN            Unreviewed;       190 AA.
AC   A6NL85; B4DNR5;
DT   24-JUL-2007, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 3.
DT   05-DEC-2018, entry version 79.
DE   SubName: Full=Interleukin-17 receptor E {ECO:0000313|Ensembl:ENSP00000406076};
DE   SubName: Full=cDNA FLJ57755, highly similar to Homo sapiens interleukin 17 receptor E (IL17RE), transcript variant 5, mRNA {ECO:0000313|EMBL:BAG60327.1};
GN   Name=IL17RE {ECO:0000313|Ensembl:ENSP00000406076};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAG60327.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000406076, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|EMBL:BAG60327.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Lung {ECO:0000313|EMBL:BAG60327.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K.,
RA   Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y.,
RA   Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M.,
RA   Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000406076}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AC018809; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AK298025; BAG60327.1; -; mRNA.
DR   UniGene; Hs.390823; -.
DR   PRIDE; A6NL85; -.
DR   Ensembl; ENST00000444427; ENSP00000406076; ENSG00000163701.
DR   UCSC; uc062goq.1; human.
DR   EuPathDB; HostDB:ENSG00000163701.18; -.
DR   HGNC; HGNC:18439; IL17RE.
DR   OpenTargets; ENSG00000163701; -.
DR   eggNOG; ENOG410IFAR; Eukaryota.
DR   eggNOG; ENOG410XTAY; LUCA.
DR   GeneTree; ENSGT00940000161421; -.
DR   HOGENOM; HOG000070033; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   Bgee; ENSG00000163701; Expressed in 94 organ(s), highest expression level in skin of leg.
DR   ExpressionAtlas; A6NL85; baseline and differential.
DR   GO; GO:0030368; F:interleukin-17 receptor activity; IEA:InterPro.
DR   InterPro; IPR039465; IL-17_rcpt-like.
DR   InterPro; IPR027841; IL-17_rcpt_C/E_N.
DR   PANTHER; PTHR15583; PTHR15583; 2.
DR   Pfam; PF15037; IL17_R_N; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Receptor {ECO:0000313|EMBL:BAG60327.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    190       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014565752.
FT   DOMAIN       41    170       IL17_R_N. {ECO:0000259|Pfam:PF15037}.
SQ   SEQUENCE   190 AA;  21231 MW;  E272DE19C12C0330 CRC64;
     MGSSRLAALL LPLLLIVIDL SDSAGIGFRH LPHWNTRCPL ASHTRKLLPR RHLSEKSHHI
     SIPSPDISHK GLRSKRTQPS DPETWESLPR LDSQRHGGPE FSFDLLPEAR AIRVTISSGP
     EVSVRLCHQW ALECEELSSP YDVQKIVSGG HTVELPYEFL LPCLCIEMAR TSGSQCTSLT
     TASTLRWSWP
//