ID   STRCL_HUMAN             Reviewed;        1772 AA.
AC   A6NGW2;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   16-JAN-2019, entry version 65.
DE   RecName: Full=Putative stereocilin-like protein;
DE   AltName: Full=Stereocilin pseudogene 1;
DE   Flags: Precursor;
GN   Name=STRCP1; Synonyms=STRCP;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M.B., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2]
RP   IDENTIFICATION.
RX   PubMed=12825070; DOI=10.1038/sj.ejhg.5200991;
RA   Avidan N., Tamary H., Dgany O., Cattan D., Pariente A., Thulliez M.,
RA   Borot N., Moati L., Barthelme A., Shalmon L., Krasnov T.,
RA   Ben-Asher E., Olender T., Khen M., Yaniv I., Zaizov R., Shalev H.,
RA   Delaunay J., Fellous M., Lancet D., Beckmann J.S.;
RT   "CATSPER2, a human autosomal nonsyndromic male infertility gene.";
RL   Eur. J. Hum. Genet. 11:497-502(2003).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the stereocilin family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. According to
CC       PubMed:12825070, no evidence has been tendered concerning the
CC       existence of this protein. {ECO:0000305}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC011330; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC018512; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   UniGene; Hs.657395; -.
DR   ProteinModelPortal; A6NGW2; -.
DR   BioMuta; HGNC:33915; -.
DR   PRIDE; A6NGW2; -.
DR   ProteomicsDB; 1159; -.
DR   GeneCards; STRCP1; -.
DR   HGNC; HGNC:33915; STRCP1.
DR   HPA; HPA048083; -.
DR   neXtProt; NX_A6NGW2; -.
DR   eggNOG; ENOG410IIWF; Eukaryota.
DR   eggNOG; ENOG410ZQVX; LUCA.
DR   HOGENOM; HOG000231838; -.
DR   HOVERGEN; HBG079223; -.
DR   InParanoid; A6NGW2; -.
DR   Proteomes; UP000005640; Unplaced.
DR   GO; GO:0009986; C:cell surface; IBA:GO_Central.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0060091; C:kinocilium; IBA:GO_Central.
DR   GO; GO:0032426; C:stereocilium tip; IBA:GO_Central.
DR   GO; GO:0007160; P:cell-matrix adhesion; IBA:GO_Central.
DR   InterPro; IPR026061; Stereocilin.
DR   InterPro; IPR026664; Stereocilin-rel.
DR   PANTHER; PTHR23412; PTHR23412; 1.
DR   PANTHER; PTHR23412:SF14; PTHR23412:SF14; 1.
PE   5: Uncertain;
KW   Complete proteome; Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL        1     25       {ECO:0000255}.
FT   CHAIN        26   1772       Putative stereocilin-like protein.
FT                                /FTId=PRO_0000339348.
FT   CARBOHYD     65     65       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    427    427       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    476    476       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    565    565       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
SQ   SEQUENCE   1772 AA;  192437 MW;  A96B4DA8FC868F97 CRC64;
     MALSLWPLLL LLLLLLLLSF AVTLAPTGPH SLDPGLSFLK SLLSTLDQAP QGSLSRSRFF
     TFLANISSSF EPGRMGEGPV GEPPPLQPPA LRLHDFLVTL RGSPDWEPML GLLGDMLALL
     GQEQTPRDFL VHQAGVLGGL VEVLLGALVP GGPPTPTQPP CTRDGPSDCV LAADWLPSLL
     LLLEGTRWQA LVQVQPSVDP TNATGLDGRE AAPHFLQGLL GLLTPTGELG SKEALWGGLL
     RTVGAPLYAA FQEGLLRVTH SLQDEVFSIL GQPEPDTNGQ CQGGNLQQLL LWGVRHNLSW
     DVQALGFLSG SPPPPPALLH CLSTGVPLPR ASQPSAHISP RQRRAITVEA LCENHLGPAP
     PYSISNFSIH LLCQHTKPAT PQPHPSTTAI CQTAVWYAVS WAPGAQGWLQ ACHDQFPDEF
     LDAICSNLSF SALSGSNRRL VKRLCAGLLP PPTSCPEGLP PVPLTPDIFW GCFLENETLW
     AERLCGEASL QAVPPSNQAW VQHVCQGPTP DVTASPPCHI GPCGERCPDG GSFLVMVCAN
     DTMYEVLVPF WPWLAGQCRI SRGGNDTCFL EGLLGPLLPS LPPLGPSPLC LTPGPFLLGM
     LSQLPRCQSS VPALAHPTRL HYLLRLLTFL LGPGAGGAEA QGMLGRALLL SSLPDNCSFW
     DAFRPEGRRS VLRTIGEYLE QDEEQPTPSG FEPTVNPSSG ISKMELLACF SPVLWDLLQR
     EKSVWALQIL VQAYLHMPPE NLQQLVLSAE REAAQGFLTL MLQGKLQGKL QVPPSEEQAL
     GRLTALLLQR YPRLTSQLFI DLSPLIPFLA VSDLMRFPPS LLANDSVLAA IRDYSPGMRP
     EQKEALAKRL LAPELFGEVP AWPQELLWAV LPLLPHLPLE NFLQLSPHQI QALEDSWPAA
     GLGPGHARHV LRSLVNQSVQ DGEEQVRRLG PLACFLSPEE LQSLVPLSDP TGPVERGLLE
     CAANGTLSPE GRVAYELLGV LRSSGGAVLS PRELRVWAPL FSQLGLRFLQ ELSEPQLRAM
     LPVLQGTSVT PAQAVLLLGR LLPRHDLSLE ELCSLHLLLP GLSPQTLQAI PRRVLVGACS
     CLAPELSRLS ACQTAALLQT FRVKDGVKNM GTTGAGPAVC IPGQQPIPTT WPDCLLPLLP
     LKLLQLDSLA LLANRRRYWE LPWSEQQAQF LWKKMQVPTN LTLRNLQALG TLAGGMSCEF
     LQQINSMVDF LEVVHMIYQL PTRVRGSLRA CIWAELQRRM AMPEPEWTTV GPELNGLDSK
     LLLDLPIQLM DRLSNESIML VVELVQRAPE QLLALTPLHQ AALAERALQN LAPKETPVSG
     EVLETLGPLV GFLGTESTRQ IPLQILLSHL SFCLGETFAT ELGWLLLQES VLGKPELWSQ
     DEVEQAGRLV FTLSTEAISL IPREALGPET LERLLEKQQS WEQSRVGQLC RGPQLAAKKA
     ALVAGVVRPA AEDLPEPVPN CADVRGTFPA ACSATQIAEM ELSDFKDCLT LFAGDPGLGP
     EEPRAAMGKA KWLWGPPRGF GPEQILQLGR LLIGLGDQEL QELILVDWGV LSTLGQIDGW
     SSTQLRIVVS SFLRQSGRHV SHLDFVHLTA LGYTLCGLRP EELQHISSWE FSQAALFLGT
     LHLQCSEEQL EFLAHLFVLP GGFGPISNWG PEIFTEIGTI AAGIPDLALS ALLRGQIQGV
     TPLAISVIPP PKFAVVFSPI QLSSLASAQA VAVTPEQMAF LSPEQRRAVA WAQHEGKESP
     EQQGRSTAWG LQDWSRPSWS LVLTISFLGH LL
//