ID   BTBDH_HUMAN             Reviewed;         478 AA.
AC   A6NE02;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JUL-2007, sequence version 1.
DT   13-FEB-2019, entry version 94.
DE   RecName: Full=BTB/POZ domain-containing protein 17;
DE   AltName: Full=Galectin-3-binding protein-like;
DE   Flags: Precursor;
GN   Name=BTBD17;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L.,
RA   Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R.,
RA   Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V.,
RA   Hannenhalli S., Turner R., Yooseph S., Lu F., Nusskern D.R.,
RA   Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H.,
RA   Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G.,
RA   Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W.,
RA   Venter J.C.;
RL   Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR   EMBL; AC103809; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471099; EAW89155.1; -; Genomic_DNA.
DR   CCDS; CCDS32719.1; -.
DR   RefSeq; NP_001073935.1; NM_001080466.1.
DR   ProteinModelPortal; A6NE02; -.
DR   SMR; A6NE02; -.
DR   iPTMnet; A6NE02; -.
DR   PhosphoSitePlus; A6NE02; -.
DR   BioMuta; BTBD17; -.
DR   PaxDb; A6NE02; -.
DR   PRIDE; A6NE02; -.
DR   ProteomicsDB; 952; -.
DR   DNASU; 388419; -.
DR   Ensembl; ENST00000375366; ENSP00000364515; ENSG00000204347.
DR   GeneID; 388419; -.
DR   KEGG; hsa:388419; -.
DR   UCSC; uc002jkn.3; human.
DR   CTD; 388419; -.
DR   EuPathDB; HostDB:ENSG00000204347.3; -.
DR   GeneCards; BTBD17; -.
DR   HGNC; HGNC:33758; BTBD17.
DR   HPA; HPA025022; -.
DR   neXtProt; NX_A6NE02; -.
DR   OpenTargets; ENSG00000204347; -.
DR   PharmGKB; PA162377627; -.
DR   eggNOG; KOG2075; Eukaryota.
DR   eggNOG; ENOG410XQ3X; LUCA.
DR   GeneTree; ENSGT00940000154858; -.
DR   HOGENOM; HOG000095275; -.
DR   HOVERGEN; HBG060469; -.
DR   InParanoid; A6NE02; -.
DR   OMA; PAWGAPW; -.
DR   OrthoDB; 1174057at2759; -.
DR   PhylomeDB; A6NE02; -.
DR   TreeFam; TF331368; -.
DR   ChiTaRS; BTBD17; human.
DR   GenomeRNAi; 388419; -.
DR   PRO; PR:A6NE02; -.
DR   Proteomes; UP000005640; Chromosome 17.
DR   Bgee; ENSG00000204347; Expressed in 35 organ(s), highest expression level in right hemisphere of cerebellum.
DR   Genevisible; A6NE02; HS.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; ISS:UniProtKB.
DR   GO; GO:0045071; P:negative regulation of viral genome replication; ISS:UniProtKB.
DR   GO; GO:0009615; P:response to virus; ISS:UniProtKB.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   SMART; SM00875; BACK; 1.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Glycoprotein; Reference proteome; Secreted; Signal.
FT   SIGNAL        1     28       {ECO:0000255}.
FT   CHAIN        29    478       BTB/POZ domain-containing protein 17.
FT                                /FTId=PRO_0000340704.
FT   DOMAIN       63    132       BTB. {ECO:0000255|PROSITE-
FT                                ProRule:PRU00037}.
FT   DOMAIN      169    269       BACK.
FT   CARBOHYD     61     61       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    100    100       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
FT   CARBOHYD    195    195       N-linked (GlcNAc...) asparagine.
FT                                {ECO:0000255}.
SQ   SEQUENCE   478 AA;  52471 MW;  A0D574BECE1A0D05 CRC64;
     MPRRGYSKPG SWGSFWAMLT LVGLVTHAAQ RADVGGEAAG TSINHSQAVL QRLQELLRQG
     NASDVVLRVQ AAGTDEVRVF HAHRLLLGLH SELFLELLSN QSEAVLQEPQ DCAAVFDKFI
     RYLYCGELTV LLTQAIPLHR LATKYGVSSL QRGVADYMRA HLAGGAGPAV GWYHYAVGTG
     DEALRESCLQ FLAWNLSAVA ASTEWGAVSP ELLWQLLQRS DLVLQDELEL FHALEAWLGR
     ARPPPAVAER ALRAIRYPMI PPAQLFQLQA RSAALARHGP AVADLLLQAY QFHAASPLHY
     AKFFDVNGSA FLPRNYLAPA WGAPWVINNP ARDDRSTSFQ TQLGPSGHDA GRRVTWNVLF
     SPRWLPVSLR PVYADAAGTA LPAARPEDGR PRLVVTPASS GGDAAGVSFQ KTVLVGARQQ
     GRLLVRHAYS FHQSSEEAGD FLAHADLQRR NSEYLVENAL HLHLIVKPVY HTLIRTPK
//