ID   A2ID99_HUMAN            Unreviewed;       178 AA.
AC   A2ID99;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   12-SEP-2018, entry version 77.
DE   SubName: Full=Rho GDP dissociation inhibitor (GDI) gamma {ECO:0000313|EMBL:CAM26353.1};
DE   SubName: Full=Rho GDP-dissociation inhibitor 3 {ECO:0000313|Ensembl:ENSP00000404435};
DE   Flags: Fragment;
GN   Name=ARHGDIG {ECO:0000313|EMBL:CAM26353.1,
GN   ECO:0000313|Ensembl:ENSP00000404435};
GN   ORFNames=LA16c-314G4.1-004 {ECO:0000313|EMBL:CAM26353.1};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:CAM26353.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000404435, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15616553; DOI=10.1038/nature03187;
RA   Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X.,
RA   Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A.,
RA   Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J.,
RA   Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L.,
RA   Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A.,
RA   Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D.,
RA   Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J.,
RA   Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M.,
RA   Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I.,
RA   Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W.,
RA   Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A.,
RA   Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S.,
RA   Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA   Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA   Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L.,
RA   Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A.,
RA   Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L.,
RA   Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N.,
RA   Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M.,
RA   Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L.,
RA   Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D.,
RA   Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P.,
RA   Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M.,
RA   Rubin E.M., Pennacchio L.A.;
RT   "The sequence and analysis of duplication-rich human chromosome 16.";
RL   Nature 432:988-994(2004).
RN   [2] {ECO:0000313|EMBL:CAM26353.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Thomas K.;
RL   Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSP00000404435}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC004754; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF510418; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; Z69667; CAM26353.1; -; Genomic_DNA.
DR   UniGene; Hs.647388; -.
DR   PRIDE; A2ID99; -.
DR   Ensembl; ENST00000447871; ENSP00000404435; ENSG00000242173.
DR   UCSC; uc059oit.1; human.
DR   EuPathDB; HostDB:ENSG00000242173.8; -.
DR   HGNC; HGNC:680; ARHGDIG.
DR   OpenTargets; ENSG00000242173; -.
DR   eggNOG; KOG3205; Eukaryota.
DR   eggNOG; ENOG4111K44; LUCA.
DR   GeneTree; ENSGT00390000006233; -.
DR   HOGENOM; HOG000175765; -.
DR   HOVERGEN; HBG000206; -.
DR   Proteomes; UP000005640; Chromosome 16.
DR   Bgee; ENSG00000242173; Expressed in 134 organ(s), highest expression level in anterior cingulate cortex.
DR   ExpressionAtlas; A2ID99; baseline and differential.
DR   GO; GO:0005829; C:cytosol; IDA:HPA.
DR   GO; GO:0005886; C:plasma membrane; IDA:HPA.
DR   GO; GO:0005094; F:Rho GDP-dissociation inhibitor activity; IEA:InterPro.
DR   Gene3D; 2.70.50.30; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR000406; Rho_GDI.
DR   InterPro; IPR024792; RhoGDI_dom_sf.
DR   PANTHER; PTHR10980; PTHR10980; 1.
DR   Pfam; PF02115; Rho_GDI; 1.
DR   PRINTS; PR00492; RHOGDI.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    178       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014083500.
FT   NON_TER     178    178       {ECO:0000313|EMBL:CAM26353.1,
FT                                ECO:0000313|Ensembl:ENSP00000404435}.
SQ   SEQUENCE   178 AA;  19627 MW;  6D588E91092ACBA4 CRC64;
     MLGLDACELG AQLLELLRLA LCARVLLADK EGGPPAVDEV LDEAVPEYRA PGRKSLLEIR
     QLDPDDRSLA KYKRVLLGPL PPAVDPSLPN VQVTRLTLLS EQAPGPVVMD LTGDLAVLKD
     QVFVLKEGVD YRVHREIVSG LKCLHHTYRR GLRVDKTVYM VGSYGPSAQE YEFVTPVE
//