ID   A2ABL0_HUMAN            Unreviewed;       147 AA.
AC   A2ABL0;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   16-JAN-2019, entry version 99.
DE   SubName: Full=Epithelial discoidin domain-containing receptor 1 {ECO:0000313|Ensembl:ENSP00000379631};
DE   Flags: Fragment;
GN   Name=DDR1 {ECO:0000313|Ensembl:ENSP00000379631};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000379631, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000379631, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=14574404; DOI=10.1038/nature02055;
RA   Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L.,
RA   Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E.,
RA   Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R.,
RA   Almeida J.P., Ambrose K.D., Andrews T.D., Ashwell R.I.S.,
RA   Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J.,
RA   Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P.,
RA   Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Carder C., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V.,
RA   Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J.,
RA   Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E.,
RA   Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A.,
RA   Frankland J., French L., Garner P., Garnett J., Ghori M.J.,
RA   Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M.,
RA   Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S.,
RA   Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R.,
RA   Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E.,
RA   Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A.,
RA   Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C.,
RA   Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M.,
RA   Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M.,
RA   Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K.,
RA   McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T.,
RA   Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R.,
RA   Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W.,
RA   Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M.,
RA   Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L.,
RA   Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J.,
RA   Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L.,
RA   Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W.,
RA   Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A.,
RA   Durbin R., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.;
RT   "The DNA sequence and analysis of human chromosome 6.";
RL   Nature 425:805-811(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000379631}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000383258}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; AL662854; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL662870; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL773541; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL773589; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL805917; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BX927194; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CR753093; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CR759747; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CR942271; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; A2ABL0; -.
DR   MaxQB; A2ABL0; -.
DR   PRIDE; A2ABL0; -.
DR   Ensembl; ENST00000396342; ENSP00000379631; ENSG00000204580.
DR   Ensembl; ENST00000400407; ENSP00000383258; ENSG00000137332.
DR   Ensembl; ENST00000400484; ENSP00000383332; ENSG00000215522.
DR   Ensembl; ENST00000445017; ENSP00000402765; ENSG00000230456.
DR   Ensembl; ENST00000453391; ENSP00000399276; ENSG00000234078.
DR   Ensembl; ENST00000454377; ENSP00000406865; ENSG00000223680.
DR   UCSC; uc063mvt.1; human.
DR   EuPathDB; HostDB:ENSG00000204580.11; -.
DR   HGNC; HGNC:2730; DDR1.
DR   OpenTargets; ENSG00000204580; -.
DR   eggNOG; KOG1094; Eukaryota.
DR   eggNOG; ENOG410XQAI; LUCA.
DR   GeneTree; ENSGT00940000159733; -.
DR   HOGENOM; HOG000197778; -.
DR   HOVERGEN; HBG105952; -.
DR   ChiTaRS; DDR1; human.
DR   Proteomes; UP000005640; Chromosome 6.
DR   Bgee; ENSG00000204580; Expressed in 230 organ(s), highest expression level in corpus callosum.
DR   ExpressionAtlas; A2ABL0; baseline and differential.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:InterPro.
DR   GO; GO:0038062; F:protein tyrosine kinase collagen receptor activity; IEA:InterPro.
DR   CDD; cd00057; FA58C; 1.
DR   Gene3D; 2.60.120.260; -; 1.
DR   InterPro; IPR029553; DDR1.
DR   InterPro; IPR000421; FA58C.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   PANTHER; PTHR24416:SF333; PTHR24416:SF333; 1.
DR   Pfam; PF00754; F5_F8_type_C; 1.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   PROSITE; PS01285; FA58C_1; 1.
DR   PROSITE; PS50022; FA58C_3; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A2ABL0,
KW   ECO:0000213|PeptideAtlas:A2ABL0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    147       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014565230.
FT   DOMAIN       31    147       F5/8 type C.
FT                                {ECO:0000259|PROSITE:PS50022}.
FT   NON_TER     147    147       {ECO:0000313|Ensembl:ENSP00000379631}.
SQ   SEQUENCE   147 AA;  16242 MW;  8C05BB12FC24A84D CRC64;
     MGPEALSSLL LLLLVASGDA DMKGHFDPAK CRYALGMQDR TIPDSDISAS SSWSDSTAAR
     HSRLESSDGD GAWCPAGSVF PKEEEYLQVD LQRLHLVALV GTQGRHAGGL GKEFSRSYRL
     RYSRDGRRWM GWKDRWGQEV ISGNEDP
//