ID   A2A3G7_HUMAN            Unreviewed;       136 AA.
AC   A2A3G7;
DT   20-FEB-2007, integrated into UniProtKB/TrEMBL.
DT   20-FEB-2007, sequence version 1.
DT   05-DEC-2018, entry version 70.
DE   SubName: Full=Guanine nucleotide exchange factor DBS {ECO:0000313|Ensembl:ENSP00000380219};
GN   Name=MCF2L {ECO:0000313|Ensembl:ENSP00000380219};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000380219, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000380219, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057823; DOI=10.1038/nature02379;
RA   Dunham A., Matthews L.H., Burton J., Ashurst J.L., Howe K.L.,
RA   Ashcroft K.J., Beare D.M., Burford D.C., Hunt S.E.,
RA   Griffiths-Jones S., Jones M.C., Keenan S.J., Oliver K., Scott C.E.,
RA   Ainscough R., Almeida J.P., Ambrose K.D., Andrews D.T.,
RA   Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R.,
RA   Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S.,
RA   Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P.,
RA   Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M.,
RA   Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J.,
RA   Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E.,
RA   Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L.,
RA   Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J.,
RA   Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S.,
RA   Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J.,
RA   Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M.,
RA   King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A.,
RA   Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S.,
RA   Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S.,
RA   Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I.,
RA   Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S.,
RA   Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A.,
RA   Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B.,
RA   Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L.,
RA   Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.,
RA   Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.;
RT   "The DNA sequence and analysis of human chromosome 13.";
RL   Nature 428:522-528(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000380219}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2012) to UniProtKB.
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DR   EMBL; AL137002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL162454; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL356740; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL596093; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A2A3G7; -.
DR   EPD; A2A3G7; -.
DR   PeptideAtlas; A2A3G7; -.
DR   PRIDE; A2A3G7; -.
DR   Ensembl; ENST00000397024; ENSP00000380219; ENSG00000126217.
DR   UCSC; uc058ykj.1; human.
DR   EuPathDB; HostDB:ENSG00000126217.20; -.
DR   HGNC; HGNC:14576; MCF2L.
DR   OpenTargets; ENSG00000126217; -.
DR   eggNOG; ENOG410IPNH; Eukaryota.
DR   eggNOG; ENOG410XNYV; LUCA.
DR   GeneTree; ENSGT00940000157874; -.
DR   HOGENOM; HOG000230921; -.
DR   ChiTaRS; MCF2L; human.
DR   Proteomes; UP000005640; Chromosome 13.
DR   Bgee; ENSG00000126217; Expressed in 195 organ(s), highest expression level in right hemisphere of cerebellum.
DR   ExpressionAtlas; A2A3G7; baseline and differential.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:A2A3G7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    136       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002642604.
SQ   SEQUENCE   136 AA;  15101 MW;  C6806888104795BB CRC64;
     MTVRRLSLLC RDLWALWLLL KAGADEIMHQ DIVPLCAADI QDQLKKRFAY LSGGRGQDGS
     PVITFPDYPA FSEIPDKEFQ NVMTYLTSIP SGGQESSIRP VSCRLTWEGC RGGLSSDVLV
     PASRKMLRMS ASHQTV
//