ID   A0A3B3ITY4_HUMAN        Unreviewed;       650 AA.
AC   A0A3B3ITY4;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   16-JAN-2019, entry version 2.
DE   SubName: Full=BMP-binding endothelial regulator protein {ECO:0000313|Ensembl:ENSP00000497982};
GN   Name=BMPER {ECO:0000313|Ensembl:ENSP00000497982};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000497982, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000497982, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000497982}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2018) to UniProtKB.
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DR   EMBL; AC007350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC010002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000650544; ENSP00000497982; ENSG00000164619.
DR   HGNC; HGNC:24154; BMPER.
DR   OpenTargets; ENSG00000164619; -.
DR   GeneTree; ENSGT00940000156485; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR002919; TIL_dom.
DR   InterPro; IPR014853; Unchr_dom_Cys-rich.
DR   InterPro; IPR001007; VWF_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   Pfam; PF08742; C8; 1.
DR   Pfam; PF01826; TIL; 1.
DR   Pfam; PF00093; VWC; 1.
DR   Pfam; PF00094; VWD; 1.
DR   SMART; SM00832; C8; 1.
DR   SMART; SM00214; VWC; 4.
DR   SMART; SM00216; VWD; 1.
DR   SUPFAM; SSF57567; SSF57567; 1.
DR   PROSITE; PS01208; VWFC_1; 1.
DR   PROSITE; PS50184; VWFC_2; 1.
DR   PROSITE; PS51233; VWFD; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A3B3ITY4,
KW   ECO:0000213|PeptideAtlas:A0A3B3ITY4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     39       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        40    650       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5017334152.
FT   DOMAIN      164    225       VWFC. {ECO:0000259|PROSITE:PS50184}.
FT   DOMAIN      328    539       VWFD. {ECO:0000259|PROSITE:PS51233}.
SQ   SEQUENCE   650 AA;  72152 MW;  0018FFA3059843F0 CRC64;
     MLWFSGVGAL AERYCRRSPG ITCCVLLLLN CSGVPMSLAS SFLTGSVAKC ENEGEVLQIP
     FITDNPCIMC VCLNKEVTCK REKCPVLSRD CALAIKQRGA CCEQCKGCTY EGNTYNSSFK
     WQSPAEPCVL RQCQEGVVTE SGVRCVVHCK NPLEHLGMCC PTCPGCVFEG VQYQEGEEFQ
     PEGSKCTKCS CTGGRTQCVR EVCPILSCPQ HLSHIPPGQC CPKCLGQRKV FDLPFGSCLF
     RSDVYDNGSS FLYDNCTACT CRDSTVVCKR KCSHPGGCDQ GQEGCCEECL LRVPPEDIKV
     CKFGNKIFQG KILNRKGCCP ICTEKPGVCT VFGDPHYNTF DGRTFNFQGT CQYVLTKDCS
     SPASPFQVLV KNDARRTRSF SWTKSVELVL GESRVSLQQH LTVRWNGSRI ALPCRAPHFH
     IDLDGYLLKV TTKAGLEISW DGDSFVEVMA APHLKGKLCG LCGNYNGHKR DDLIGGDGNF
     KFDVDDFAES WRVESNEFCN RPQRKPVPEL CQGTVKVKLR AHRECQKLKS WEFQTCHSTV
     DYATFYRSCV TDMCECPVHK NCYCESFLAY TRACQREGIK VHWEPQQNCA ATQCKHGAVY
     DTCGPGCIKT CDNWNEIGPC NKPCVAGCHC PANLVLHKGR CIKPVLCPQR
//