ID   A0A3B3ITE8_HUMAN        Unreviewed;       401 AA.
AC   A0A3B3ITE8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   16-JAN-2019, entry version 2.
DE   SubName: Full=Procollagen C-endopeptidase enhancer 2 {ECO:0000313|Ensembl:ENSP00000497763};
GN   Name=PCOLCE2 {ECO:0000313|Ensembl:ENSP00000497763};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000497763, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000497763, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R.,
RA   Buhay C.J., Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R.,
RA   Gunaratne P., Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V.,
RA   Hume J., Jackson A., Khan Z.M., Kovar-Smith C., Lewis L.R.,
RA   Lozado R.J., Metzker M.L., Milosavljevic A., Miner G.R., Morgan M.B.,
RA   Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., Wei S.,
RA   Wheeler D.A., Wright M.W., Worley K.C., Yuan Y., Zhang Z., Adams C.Q.,
RA   Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z.,
RA   Clendenning J., Clerc-Blankenburg K.P., Chen R., Chen Z., Davis C.,
RA   Delgado O., Dinh H.H., Dong W., Draper H., Ernst S., Fu G.,
RA   Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J., Hao B.,
RA   Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W., Jackson L.R.,
RA   Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B., Liu J.,
RA   Liu W., Lu J., Maheshwari M., Nguyen B.V., Okwuonu G.O., Palmeiri A.,
RA   Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K., Yao Z., Zhang J.,
RA   Zhang X., Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H.,
RA   Reinhardt R., Naylor S.L., Yang H., Olson M., Weinstock G.,
RA   Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000497763}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2018) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00059}.
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DR   EMBL; AC021074; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC022291; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000648195; ENSP00000497763; ENSG00000163710.
DR   HGNC; HGNC:8739; PCOLCE2.
DR   OpenTargets; ENSG00000163710; -.
DR   GeneTree; ENSGT00940000157649; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   CDD; cd00041; CUB; 2.
DR   Gene3D; 2.60.120.290; -; 2.
DR   InterPro; IPR000859; CUB_dom.
DR   InterPro; IPR035914; Sperma_CUB_dom_sf.
DR   Pfam; PF00431; CUB; 2.
DR   SMART; SM00042; CUB; 2.
DR   SUPFAM; SSF49854; SSF49854; 2.
DR   PROSITE; PS01180; CUB; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00059,
KW   ECO:0000256|SAAS:SAAS01008102};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A3B3ITE8,
KW   ECO:0000213|PeptideAtlas:A0A3B3ITE8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    401       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5017437612.
FT   DOMAIN       33    144       CUB. {ECO:0000259|PROSITE:PS01180}.
FT   DOMAIN      154    268       CUB. {ECO:0000259|PROSITE:PS01180}.
FT   DISULFID    154    181       {ECO:0000256|PROSITE-ProRule:PRU00059}.
SQ   SEQUENCE   401 AA;  44672 MW;  CDD46F47B4FA9F7B CRC64;
     MRGANAWAPL CLLLAAATQL SRQQSPERPV FTCGGILTGE SGFIGSEGFP GVYPPNSKCT
     WKITVPEGKV VVLNFRFIDL ESDNLCRYDF VDVYNGHANG QRIGRFCGTF RPGALVSSGN
     KMMVQMISDA NTAGNGFMAM FSAAEPNERG DQYCGGLLDR PSGSFKTPNW PDRDYPAGVT
     CVWHIVAPKN QLIELKFEKF DVERDNYCRY DYVAVFNGGE VNDARRIGKY CGDSPPAPIV
     SERNELLIQF LSDLSLTADG FIGHYIFRPK KLPTTTEQPV TTTFPVTTGL KPTVALCQQK
     CRRTGTLEGN YCSSDFVLLA FAFTVTSLQN VFFCSISRHC YHNHHSRWEF ARHSLDHQHL
     QRGKFGDSAG GQEHECQADC RLQAVPSPQK RSKLHYYGPS R
//