ID   A0A3B3ISW8_HUMAN        Unreviewed;        77 AA.
AC   A0A3B3ISW8;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   13-FEB-2019, entry version 3.
DE   RecName: Full=Serum amyloid A protein {ECO:0000256|RuleBase:RU000539};
GN   Name=SAA1 {ECO:0000313|Ensembl:ENSP00000497498};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000497498, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000497498, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000497498}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2018) to UniProtKB.
CC   -!- FUNCTION: Major acute phase reactant. Apolipoprotein of the HDL
CC       complex. {ECO:0000256|RuleBase:RU000539}.
CC   -!- SIMILARITY: Belongs to the SAA family.
CC       {ECO:0000256|RuleBase:RU000539}.
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DR   EMBL; AC107948; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000649195; ENSP00000497498; ENSG00000173432.
DR   HGNC; HGNC:10513; SAA1.
DR   OpenTargets; ENSG00000173432; -.
DR   GeneTree; ENSGT00390000004737; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   GO; GO:0034364; C:high-density lipoprotein particle; IEA:UniProtKB-UniRule.
DR   GO; GO:0006953; P:acute-phase response; IEA:UniProtKB-UniRule.
DR   InterPro; IPR000096; Serum_amyloid_A.
DR   Pfam; PF00277; SAA; 1.
DR   PRINTS; PR00306; SERUMAMYLOID.
DR   SMART; SM00197; SAA; 1.
DR   PROSITE; PS00992; SAA; 1.
PE   1: Evidence at protein level;
KW   Acute phase {ECO:0000256|RuleBase:RU000539};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   HDL {ECO:0000256|RuleBase:RU000539};
KW   Proteomics identification {ECO:0000213|EPD:A0A3B3ISW8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19     77       Serum amyloid A protein.
FT                                {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5017307095.
SQ   SEQUENCE   77 AA;  8508 MW;  6C6220EF192476E4 CRC64;
     MKLLTGLVFC SLVLGVSSRS FFSFLGEAFD GARDMWRAYS DMREANYIGS DKYFHARGNY
     DAAKRGPGGA WAAEVIT
//