ID   A0A3B3ISL7_HUMAN        Unreviewed;       592 AA.
AC   A0A3B3ISL7;
DT   05-DEC-2018, integrated into UniProtKB/TrEMBL.
DT   05-DEC-2018, sequence version 1.
DT   16-JAN-2019, entry version 2.
DE   SubName: Full=BMP-binding endothelial regulator protein {ECO:0000313|Ensembl:ENSP00000497488};
GN   Name=BMPER {ECO:0000313|Ensembl:ENSP00000497488};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000497488, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000497488, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000497488}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (OCT-2018) to UniProtKB.
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DR   EMBL; AC007350; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC010002; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000648392; ENSP00000497488; ENSG00000164619.
DR   HGNC; HGNC:24154; BMPER.
DR   OpenTargets; ENSG00000164619; -.
DR   GeneTree; ENSGT00940000156485; -.
DR   Proteomes; UP000005640; Chromosome 7.
DR   InterPro; IPR036084; Ser_inhib-like_sf.
DR   InterPro; IPR002919; TIL_dom.
DR   InterPro; IPR014853; Unchr_dom_Cys-rich.
DR   InterPro; IPR001007; VWF_dom.
DR   InterPro; IPR001846; VWF_type-D.
DR   Pfam; PF08742; C8; 1.
DR   Pfam; PF01826; TIL; 1.
DR   Pfam; PF00093; VWC; 1.
DR   Pfam; PF00094; VWD; 1.
DR   SMART; SM00832; C8; 1.
DR   SMART; SM00214; VWC; 4.
DR   SMART; SM00216; VWD; 1.
DR   SUPFAM; SSF57567; SSF57567; 1.
DR   PROSITE; PS01208; VWFC_1; 1.
DR   PROSITE; PS50184; VWFC_2; 1.
DR   PROSITE; PS51233; VWFD; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A3B3ISL7,
KW   ECO:0000213|PeptideAtlas:A0A3B3ISL7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     39       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        40    592       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5017249284.
FT   DOMAIN      164    225       VWFC. {ECO:0000259|PROSITE:PS50184}.
FT   DOMAIN      299    481       VWFD. {ECO:0000259|PROSITE:PS51233}.
SQ   SEQUENCE   592 AA;  65791 MW;  224833ED4DA57462 CRC64;
     MLWFSGVGAL AERYCRRSPG ITCCVLLLLN CSGVPMSLAS SFLTGSVAKC ENEGEVLQIP
     FITDNPCIMC VCLNKEVTCK REKCPVLSRD CALAIKQRGA CCEQCKGCTY EGNTYNSSFK
     WQSPAEPCVL RQCQEGVVTE SGVRCVVHCK NPLEHLGMCC PTCPGCVFEG VQYQEGEEFQ
     PEGSKCTKCS CTGGRTQCVR EVCPILSCPQ HLSHIPPGQC CPKCLGQRKV FDLPFGSCLF
     RSDVYDNGSS FLYDNCTACT CRDSTVVCKR KCSHPGGCDQ GQEGCCEECL LRVPPEDIKV
     CKFGNKIFQV LVKNDARRTR SFSWTKSVEL VLGESRVSLQ QHLTVRWNGS RIALPCRAPH
     FHIDLDGYLL KVTTKAGLEI SWDGDSFVEV MAAPHLKGKL CGLCGNYNGH KRDDLIGGDG
     NFKFDVDDFA ESWRVESNEF CNRPQRKPVP ELCQGTVKVK LRAHRECQKL KSWEFQTCHS
     TVDYATFYRS CVTDMCECPV HKNCYCESFL AYTRACQREG IKVHWEPQQN CAATQCKHGA
     VYDTCGPGCI KTCDNWNEIG PCNKPCVAGC HCPANLVLHK GRCIKPVLCP QR
//