ID   A0A2U3TZL5_HUMAN        Unreviewed;       120 AA.
AC   A0A2U3TZL5;
DT   18-JUL-2018, integrated into UniProtKB/TrEMBL.
DT   18-JUL-2018, sequence version 1.
DT   13-FEB-2019, entry version 4.
DE   SubName: Full=CD59 glycoprotein {ECO:0000313|Ensembl:ENSP00000434617};
DE   Flags: Fragment;
GN   Name=CD59 {ECO:0000313|Ensembl:ENSP00000434617};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000434617, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000434617, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000434617}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2018) to UniProtKB.
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DR   EMBL; AL049629; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000528700; ENSP00000434617; ENSG00000085063.
DR   HGNC; HGNC:1689; CD59.
DR   OpenTargets; ENSG00000085063; -.
DR   GeneTree; ENSGT00390000016309; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   ExpressionAtlas; A0A2U3TZL5; baseline and differential.
DR   GO; GO:0001971; P:negative regulation of activation of membrane attack complex; IEA:InterPro.
DR   InterPro; IPR018363; CD59_antigen_CS.
DR   InterPro; IPR027101; CD59_glyco.
DR   InterPro; IPR016054; LY6_UPA_recep-like.
DR   PANTHER; PTHR10036:SF9; PTHR10036:SF9; 1.
DR   Pfam; PF00021; UPAR_LY6; 1.
DR   SMART; SM00134; LU; 1.
DR   PROSITE; PS00983; LY6_UPAR; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    120       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5015458801.
FT   DOMAIN       26    108       UPAR/Ly6. {ECO:0000259|SMART:SM00134}.
FT   NON_TER     120    120       {ECO:0000313|Ensembl:ENSP00000434617}.
SQ   SEQUENCE   120 AA;  13343 MW;  E3CEA0BC00CC12C9 CRC64;
     MGIQGGSVLF GLLLVLAVFC HSGHSLQCYN CPNPTADCKT AVNCSSDFDA CLITKAGLQV
     YNKCWKFEHC NFNDVTTRLR ENELTYYCCK KDLCNFNEQL ENGGTSLSEK TVLLLVTPFL
//