ID   A0A2R8YCK4_HUMAN        Unreviewed;        81 AA.
AC   A0A2R8YCK4;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   13-FEB-2019, entry version 4.
DE   SubName: Full=Tripeptidyl-peptidase 1 {ECO:0000313|Ensembl:ENSP00000493706};
GN   Name=TPP1 {ECO:0000313|Ensembl:ENSP00000493706};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000493706, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000493706, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000493706}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2018) to UniProtKB.
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DR   EMBL; AC091564; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000531754; ENSP00000493706; ENSG00000166340.
DR   HGNC; HGNC:2073; TPP1.
DR   OpenTargets; ENSG00000166340; -.
DR   GeneTree; ENSGT00390000008684; -.
DR   Proteomes; UP000005640; Chromosome 11.
DR   ExpressionAtlas; A0A2R8YCK4; baseline and differential.
DR   GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR   InterPro; IPR015366; S53_propep.
DR   Pfam; PF09286; Pro-kuma_activ; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A2R8YCK4,
KW   ECO:0000213|PeptideAtlas:A0A2R8YCK4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22     81       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5015306387.
FT   DOMAIN       33     81       Pro-kuma_activ.
FT                                {ECO:0000259|Pfam:PF09286}.
SQ   SEQUENCE   81 AA;  8938 MW;  456FC48909ECFD7D CRC64;
     MGLQACLLGL FALILSGKCS YSPEPDQRRT LPPGWVSLGR ADPEEELSLT FALRQQNVER
     LSELVQAVSD PSSPQYGAFW D
//