ID   A0A2R8Y5Y0_HUMAN        Unreviewed;       438 AA.
AC   A0A2R8Y5Y0;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   05-DEC-2018, entry version 5.
DE   SubName: Full=Killer cell immunoglobulin-like receptor 2DL5A {ECO:0000313|Ensembl:ENSP00000496082};
DE   SubName: Full=Killer cell immunoglobulin-like receptor 2DL5B {ECO:0000313|Ensembl:ENSP00000494875};
DE   SubName: Full=Killer cell immunoglobulin-like receptor 3DS1 {ECO:0000313|Ensembl:ENSP00000494907};
GN   Name=KIR3DS1 {ECO:0000313|Ensembl:ENSP00000494907};
GN   Synonyms=KIR2DL5A {ECO:0000313|Ensembl:ENSP00000496082},
GN   KIR2DL5B {ECO:0000313|Ensembl:ENSP00000494875};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000494907, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000494907, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000494907}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2018) to UniProtKB.
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DR   EMBL; KP420440; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KU645196; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KU645197; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000642211; ENSP00000494907; ENSG00000283719.
DR   Ensembl; ENST00000642588; ENSP00000494875; ENSG00000284301.
DR   Ensembl; ENST00000642998; ENSP00000496082; ENSG00000283889.
DR   Ensembl; ENST00000644214; ENSP00000494924; ENSG00000284111.
DR   Ensembl; ENST00000644640; ENSP00000496120; ENSG00000283889.
DR   Ensembl; ENST00000645203; ENSP00000496469; ENSG00000284111.
DR   Ensembl; ENST00000645422; ENSP00000495116; ENSG00000284301.
DR   Ensembl; ENST00000646179; ENSP00000496320; ENSG00000283719.
DR   HGNC; HGNC:16345; KIR2DL5A.
DR   HGNC; HGNC:16346; KIR2DL5B.
DR   HGNC; HGNC:6340; KIR3DS1.
DR   Proteomes; UP000005640; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 3.
DR   SMART; SM00409; IG; 3.
DR   SUPFAM; SSF48726; SSF48726; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    438       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5016513048.
FT   TRANSMEM    339    360       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    118       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      129    209       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      229    316       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   438 AA;  48717 MW;  9798E6195566509D CRC64;
     MLLMVVSMAC VGLFLVQRAG PHMGGQDKPF LSAWPSAVVP RGGHVTLRCH YRHRFNNFML
     YKEDRIHVPI FHGRIFQEGF NMSPVTTAHA GNYTCRGSHP HSPTGWSAPS NPMVIMVTGN
     HRKPSLLAHP GPLVKSGERV ILQCWSDIMF EHFFLHKEWI SKDPSRLVGQ IHDGVSKANF
     SIGSMMRALA GTYRCYGSVT HTPYQLSAPS DPLDIVVTGL YEKPSLSAQP GPKVQAGESV
     TLSCSSRSSY DMYHLSREGG AHERRLPAVR KVNRTFQADF PLGPATHGGT YRCFGSFRHS
     PYEWSDPSDP LLVSVTGNPS SSWPSPTEPS SKSGNLRHLH ILIGTSVVKI PFTILLFFLL
     HRWCSNKKNA AVMDQEPAGD RTVNREDSDD QDPQEVTYAQ LDHCVFTQTK ITSPSQRPKT
     PPTDTTMYME LPNAKPRS
//