ID   A0A2R8Y3T5_HUMAN        Unreviewed;       730 AA.
AC   A0A2R8Y3T5;
DT   20-JUN-2018, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 1.
DT   05-DEC-2018, entry version 4.
DE   SubName: Full=Leishmanolysin-like peptidase 2 {ECO:0000313|Ensembl:ENSP00000493582};
GN   Name=LMLN2 {ECO:0000313|Ensembl:ENSP00000493582};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000493582, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000493582, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000493582}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2018) to UniProtKB.
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DR   EMBL; AL117258; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000644000; ENSP00000493582; ENSG00000283654.
DR   HGNC; HGNC:53647; LMLN2.
DR   GeneTree; ENSGT00940000163573; -.
DR   Proteomes; UP000005640; Chromosome 14.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR001577; Peptidase_M8.
DR   PANTHER; PTHR10942; PTHR10942; 1.
DR   Pfam; PF01457; Peptidase_M8; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    730       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5015341228.
FT   TRANSMEM    678    698       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   730 AA;  79252 MW;  1DE976EE582ED042 CRC64;
     MLLLLLLLLL LPPLVLRVAA SRCLHDETQK SVSLLRPPFS QLPSKSRSSS LTLPSSRDPQ
     PLRIQSCYLG DHISDGAWDP EGEGMRGGSR ALAAVREATQ RIQAVLAVQG PLLLSRDPAQ
     YCHAVWGDPD SPNYHRCSLL NPGYKGESCL GAKIPDTHLR GYALWPEQGP PQLVQPDGPG
     VQNTDFLLYV RVAHTSKCHQ EPSVIAYAAC CQLDSEDRPL AGTIVYCAQH LTSPSLSHSD
     IVMATLHELL HALGFSGQLF KKWRDCPSGF SVRENCSTRQ LVTRQDEWGQ LLLTTPAVSL
     SLAKHLGVSG ASLGVPLEEE EGLLSSHWEA RLLQGSLMTA TFDGAQRTRL DPITLAAFKD
     SGWYQVNHSA AEELLWGQGS GPEFGLVTTC GTGSSDFFCT GSGLGCHYLH LDKGSCSSDP
     MLEGCRMYKP LANGSECWKK ENGFPAGVDN PHGEIYHPQS RCFFANLTSQ LLPGDKPRHP
     SLTPHLKEAE LMGRCYLHQC TGRGAYKVQV EGSPWVPCLP GKVIQIPGYY GLLFCPRGRL
     CQTNEDINAV TSPPVSLSTP DPLFQLSLEL AGPPGHSLGK EQQEGLAEAV LEALASKGGT
     GRCYFHGPSI TTSLVFTVHM WKSPGCQGPS VATLHKALTL TLQKKPLEVY HGGANFTTQP
     SKLLVTSDHN PSMTHLRLSM GLCLMLLILV GVMGTTAYQK RATLPVRPSA SYHSPELHST
     RVPVRGIREV
//