ID   A0A1W2PQV0_HUMAN        Unreviewed;       398 AA.
AC   A0A1W2PQV0;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   16-JAN-2019, entry version 8.
DE   SubName: Full=Killer cell immunoglobulin-like receptor 2DL4 {ECO:0000313|Ensembl:ENSP00000492338};
DE   Flags: Fragment;
GN   Name=KIR2DL4 {ECO:0000313|Ensembl:ENSP00000492338};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000492338, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000492338, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000492338}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
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DR   EMBL; KP420438; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KP420445; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KU645195; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; A0A1W2PQV0; -.
DR   Ensembl; ENST00000639635; ENSP00000492338; ENSG00000284509.
DR   Ensembl; ENST00000639882; ENSP00000492327; ENSG00000283869.
DR   Ensembl; ENST00000640090; ENSP00000491009; ENSG00000284460.
DR   HGNC; HGNC:6332; KIR2DL4.
DR   Proteomes; UP000005640; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 2.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; SSF48726; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A1W2PQV0,
KW   ECO:0000213|PeptideAtlas:A0A1W2PQV0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23    398       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014069030.
FT   TRANSMEM    243    261       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       35    119       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      130    217       IG. {ECO:0000259|SMART:SM00409}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000492338}.
SQ   SEQUENCE   398 AA;  43669 MW;  C9E272E0D591FA21 CRC64;
     XMSPTVIILA CLGFFLDQSV WAHVGGQDKP FCSAWPSAVV PQGGHVTLRC HCRRGFNIFT
     LYKKDGVPVP ELYNRIFWNS FLISPVTPAH AGTYRCRGFH PHSPTEWSAP SNPLVIMVTG
     LYEKPSLTAR PGPTVRAGEN VTLSCSSQSS FDIYHLSREG EAHELRLPAV PSINGTFQAD
     FPLGPATHGE TYRCFGSFHG SPYEWSDPSD PLPVSVTGNP SSSWPSPTEP SFKTGIARHL
     HAVIRYSVAI ILFTILPFFL LHRWCSKKKV SLTKQRPENS GPCAEAGWEH ADAAVMNQEP
     AGHRTVNRED SDEQDPQEVT YAQLDHCIFT QRKITGPSQR SKRPSTDTSV CIELPNAEPR
     ALSPAHEHHS QALMGSSRET TALSQTQLAS SNVPAAGI
//