ID   A0A1W2PQ83_HUMAN        Unreviewed;       454 AA.
AC   A0A1W2PQ83;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   28-MAR-2018, entry version 6.
DE   SubName: Full=Killer cell immunoglobulin-like receptor 2DS4 {ECO:0000313|Ensembl:ENSP00000491824};
GN   Name=KIR2DS4 {ECO:0000313|Ensembl:ENSP00000491824};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000491824, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000491824, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000491824}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
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DR   EMBL; CU464060; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CU464062; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000638649; ENSP00000491824; ENSG00000274921.
DR   HGNC; HGNC:6336; KIR2DS4.
DR   Proteomes; UP000005640; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 3.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 2.
DR   SUPFAM; SSF48726; SSF48726; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    454       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5011986502.
FT   TRANSMEM    339    360       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    118       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN       40    102       IGc2. {ECO:0000259|SMART:SM00408}.
FT   DOMAIN      129    209       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      135    202       IGc2. {ECO:0000259|SMART:SM00408}.
FT   DOMAIN      229    316       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   454 AA;  50134 MW;  EE9A7E045ABFAF4A CRC64;
     MSLMVVSMAC VGFFLLQGAW THEGGQDKPF LSAWPSPVVS EGEHVALQCR SRLGFNEFSL
     SKEDGMPVPE LYNRVFRNTV FIGPVTPAHA GTYRCRGSHP HFLTGWSAPS NPLVIMVTGV
     HRKPSLLAHP GPLVKSEETV ILQCWSDVMF EHFLLHREGK FNDTLRLTGE LHDGVSKANF
     SIGRMTQDLA GTYRCYGSVP HSPYQLSAPS DPLDIVITGL CGKPSLSAQP RPMVKAGESV
     TLSCSSRSSY DIYHLSREGE AHERRLPAVR SINGTFQADF PLGPATHGGT YRCFGSFRDA
     PYEWSNSSDP LLVSVTGNPS NSWPSPTEPS SKTGNPRHLH VLIGTSVVKI PFTILLFFLL
     HRWCSDKKNA AVMDQEPAGN RTVNSEDSDE QDHQEVSYAL DHCVFTQRKI TRPSERPKTP
     PTDTSMYIEL PNAEPRSKVV FCPRAPQSGL EGIF
//