ID   A0A1W2PPQ7_HUMAN        Unreviewed;       393 AA.
AC   A0A1W2PPQ7;
DT   07-JUN-2017, integrated into UniProtKB/TrEMBL.
DT   07-JUN-2017, sequence version 1.
DT   16-JAN-2019, entry version 8.
DE   SubName: Full=GPI transamidase component PIG-T {ECO:0000313|Ensembl:ENSP00000491534};
DE   Flags: Fragment;
GN   Name=PIGT {ECO:0000313|Ensembl:ENSP00000491534};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000491534, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000491534, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11780052; DOI=10.1038/414865a;
RA   Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R.,
RA   Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L.,
RA   Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M.,
RA   Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M., Brown A.J.,
RA   Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P.,
RA   Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M.,
RA   Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R.,
RA   Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M.,
RA   Ellington A.G., Frankland J.A., Fraser A., French L., Garner P.,
RA   Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E.,
RA   Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J.,
RA   Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D.,
RA   Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S.,
RA   Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D.,
RA   Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A.,
RA   Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T.,
RA   Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I.,
RA   Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H.,
RA   Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S.,
RA   Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E.,
RA   Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A.,
RA   Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M.,
RA   Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A.,
RA   Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S.,
RA   Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 20.";
RL   Nature 414:865-871(2001).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000213|PubMed:25944712}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=25944712;
RA   Vaca Jacome A.S., Rabilloud T., Schaeffer-Reiss C., Rompais M.,
RA   Ayoub D., Lane L., Bairoch A., Van Dorsselaer A., Carapito C.;
RT   "N-terminome analysis of the human mitochondrial proteome.";
RL   Proteomics 15:2519-2524(2015).
RN   [4] {ECO:0000313|Ensembl:ENSP00000491534}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
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DR   EMBL; AL021578; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL031663; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; A0A1W2PPQ7; -.
DR   PeptideAtlas; A0A1W2PPQ7; -.
DR   Ensembl; ENST00000639382; ENSP00000491534; ENSG00000124155.
DR   HGNC; HGNC:14938; PIGT.
DR   OpenTargets; ENSG00000124155; -.
DR   GeneTree; ENSGT00390000018558; -.
DR   ChiTaRS; PIGT; human.
DR   Proteomes; UP000005640; Chromosome 20.
DR   ExpressionAtlas; A0A1W2PPQ7; baseline and differential.
DR   GO; GO:0042765; C:GPI-anchor transamidase complex; IEA:InterPro.
DR   GO; GO:0016255; P:attachment of GPI anchor to protein; IEA:InterPro.
DR   InterPro; IPR007245; PIG-T.
DR   PANTHER; PTHR12959; PTHR12959; 2.
DR   Pfam; PF04113; Gpi16; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|EPD:A0A1W2PPQ7,
KW   ECO:0000213|MaxQB:A0A1W2PPQ7, ECO:0000213|PeptideAtlas:A0A1W2PPQ7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    393       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5010711602.
FT   NON_TER     393    393       {ECO:0000313|Ensembl:ENSP00000491534}.
SQ   SEQUENCE   393 AA;  44630 MW;  F0298CA4FB10BD1B CRC64;
     MAAAMPLALL VLLLLGPGGW CLAEPPRDSL REELVITPLP SGDVAATFQF RTRWDSELQR
     EGVSHYRLFP KALGQLISKY SLRELHLSFT QGFWRTRYWG PPFLQAPSVW INLGRSSVMS
     SQGSSAPLST SSTPPTQSLP LPPSNPWVWP MAGLSVLLKA DRLFHTSYHS QAVHIRPVCR
     NARCTSISWE LRQTLSVVFD AFITGQGKKD WSLFRMFSRT LTEPCPLASE SRVYVDITTY
     NQDNETLEVH PPPTTTYQDV ILGTRKTYAI YDLLDTAMIN NSRNLNIQLK WKRPPENEAP
     PVPFLHAQRY VSGYGLQKGE LSTLLYNTHP YRAFPVLLLD TVPWYLRLYV HTLTITSKGK
     ENKPSYIHYQ PAQDRLQPHL LEMLIQLPAN SVT
//