ID   A0A1B0GVP9_HUMAN        Unreviewed;        81 AA.
AC   A0A1B0GVP9;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   05-DEC-2018, entry version 12.
DE   SubName: Full=Neuronal acetylcholine receptor subunit alpha-7 {ECO:0000313|Ensembl:ENSP00000490605};
GN   Name=CHRNA7 {ECO:0000313|Ensembl:ENSP00000490605};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000490605, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000490605, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16572171; DOI=10.1038/nature04601;
RA   Zody M.C., Garber M., Sharpe T., Young S.K., Rowen L., O'Neill K.,
RA   Whittaker C.A., Kamal M., Chang J.L., Cuomo C.A., Dewar K.,
RA   FitzGerald M.G., Kodira C.D., Madan A., Qin S., Yang X., Abbasi N.,
RA   Abouelleil A., Arachchi H.M., Baradarani L., Birditt B., Bloom S.,
RA   Bloom T., Borowsky M.L., Burke J., Butler J., Cook A., DeArellano K.,
RA   DeCaprio D., Dorris L. III, Dors M., Eichler E.E., Engels R.,
RA   Fahey J., Fleetwood P., Friedman C., Gearin G., Hall J.L., Hensley G.,
RA   Johnson E., Jones C., Kamat A., Kaur A., Locke D.P., Madan A.,
RA   Munson G., Jaffe D.B., Lui A., Macdonald P., Mauceli E., Naylor J.W.,
RA   Nesbitt R., Nicol R., O'Leary S.B., Ratcliffe A., Rounsley S., She X.,
RA   Sneddon K.M., Stewart S., Sougnez C., Stone S.M., Topham K.,
RA   Vincent D., Wang S., Zimmer A.R., Birren B.W., Hood L., Lander E.S.,
RA   Nusbaum C.;
RT   "Analysis of the DNA sequence and duplication history of human
RT   chromosome 15.";
RL   Nature 440:671-675(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000490605}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2016) to UniProtKB.
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DR   EMBL; ABBA01038340; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC058803; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC068448; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC079969; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456018; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF456023; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF573652; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENST00000635722; ENSP00000490605; ENSG00000175344.
DR   HGNC; HGNC:1960; CHRNA7.
DR   OpenTargets; ENSG00000175344; -.
DR   GeneTree; ENSGT00940000154617; -.
DR   ChiTaRS; CHRNA7; human.
DR   Proteomes; UP000005640; Chromosome 15.
DR   ExpressionAtlas; A0A1B0GVP9; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   GO; GO:0005230; F:extracellular ligand-gated ion channel activity; IEA:InterPro.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   Gene3D; 2.70.170.10; -; 1.
DR   InterPro; IPR006202; Neur_chan_lig-bd.
DR   InterPro; IPR036734; Neur_chan_lig-bd_sf.
DR   InterPro; IPR006201; Neur_channel.
DR   PANTHER; PTHR18945; PTHR18945; 1.
DR   Pfam; PF02931; Neur_chan_LBD; 1.
DR   SUPFAM; SSF63712; SSF63712; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     22       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        23     81       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008408669.
FT   DOMAIN       27     65       Neur_chan_LBD.
FT                                {ECO:0000259|Pfam:PF02931}.
SQ   SEQUENCE   81 AA;  9096 MW;  1FAD1D87748EA921 CRC64;
     MRCSPGGVWL ALAASLLHVS LQGEFQRKLY KELVKNYNPL ERPVANDSQP LTVYFSLSLL
     QIMDVILRIN KKTDSICSGL C
//