ID   A0A191URJ0_HUMAN        Unreviewed;       341 AA.
AC   A0A191URJ0;
DT   05-OCT-2016, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2016, sequence version 1.
DT   25-APR-2018, entry version 10.
DE   SubName: Full=KIR2DL3 {ECO:0000313|EMBL:CDX48183.1};
DE   SubName: Full=Killer cell immunoglobulin-like receptor 2DL3 {ECO:0000313|Ensembl:ENSP00000490973};
DE   SubName: Full=Killer cell immunoglobulin-like receptor two domains long cytoplasmic tail 3 {ECO:0000313|EMBL:ANJ04810.1};
GN   Name=KIR2DL3 {ECO:0000313|EMBL:ANJ04810.1,
GN   ECO:0000313|Ensembl:ENSP00000490973};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:ANJ04810.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000490973, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|EMBL:CDX48183.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Nemat-Gorgani N., Norman P.J., Parham P.;
RT   "KIR Diversity in Africans.";
RL   Submitted (JUL-2014) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|EMBL:ANJ04810.1}
RP   NUCLEOTIDE SEQUENCE.
RA   Roe D., Vierra-Green C., Pyo C.-W., Eng K., Hall R., Spellman S.,
RA   Ranade S., Geraghty D.E., Maiers M.;
RT   "Full Haplotype Sequences of the Killer Immunoglobulin-like Receptor
RT   (KIR) Region in Several Diverse Diploid Individuals using Single
RT   Molecule, Real-Time Sequencing.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|Ensembl:ENSP00000490973}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
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DR   EMBL; KU645198; ANJ04810.1; -; Genomic_DNA.
DR   EMBL; LM656211; CDX48183.1; -; Genomic_DNA.
DR   UniGene; Hs.654608; -.
DR   UniGene; Hs.731378; -.
DR   PeptideAtlas; A0A191URJ0; -.
DR   Ensembl; ENST00000640389; ENSP00000490973; ENSG00000284044.
DR   HGNC; HGNC:6331; KIR2DL3.
DR   ChiTaRS; KIR2DL3; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 2.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; SSF48726; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Receptor {ECO:0000313|EMBL:ANJ04810.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    341       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014046676.
FT   TRANSMEM    244    265       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    114       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      134    221       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   341 AA;  37902 MW;  A6457C0ED18BC915 CRC64;
     MSLMVVSMAC VGFFLLQGAW PHEGVHRKPS LRAHPGPLVK SEETVILQCW SDVRFEHFLL
     HREGKFKDTL RLIGEHHDGV SKANFSIGPM MQDLAGTYRC YGSVTHSPYQ LSAPSDPLDI
     VITGLYEKPS LSAQPGPTVL AGESVTLSCS SRSSYDMYHL SREGEAHERR FSAGPKVNGT
     FQADFPLGPA THGGTYRCFG SFRDSPYEWS NSSDPLLVSV TGNPSNSWPS PTEPSSETGN
     PRHLHVLIGT SVVIILFILL LFFLLHRWCC NKKNAVVMDQ EPAGNRTVNR EDSDEQDPQE
     VTYAQLNHCV FTQRKITHPS QRPKTPPTDI IVYTELPNAE P
//