ID   A0A182DWH7_HUMAN        Unreviewed;       310 AA.
AC   A0A182DWH7;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   16-JAN-2019, entry version 9.
DE   SubName: Full=Selenoprotein P {ECO:0000313|Ensembl:ENSP00000421626};
DE   Flags: Fragment;
GN   Name=SELENOP {ECO:0000313|Ensembl:ENSP00000421626};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000421626, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000421626, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15372022; DOI=10.1038/nature02919;
RA   Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S.,
RA   Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M.,
RA   She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.,
RA   Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M.,
RA   Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T.,
RA   Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M.,
RA   Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K.,
RA   Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C.,
RA   Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M.,
RA   Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A.,
RA   Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M.,
RA   Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M.,
RA   Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S.,
RA   Richardson P., Lucas S.M., Myers R.M., Rubin E.M.;
RT   "The DNA sequence and comparative analysis of human chromosome 5.";
RL   Nature 431:268-274(2004).
RN   [2] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
RN   [3] {ECO:0000313|Ensembl:ENSP00000421626}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2016) to UniProtKB.
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DR   EMBL; AC008945; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; A0A182DWH7; -.
DR   PeptideAtlas; A0A182DWH7; -.
DR   Ensembl; ENST00000514218; ENSP00000421626; ENSG00000250722.
DR   HGNC; HGNC:10751; SELENOP.
DR   OpenTargets; ENSG00000250722; -.
DR   GeneTree; ENSGT00510000049326; -.
DR   ChiTaRS; SELENOP; human.
DR   Proteomes; UP000005640; Chromosome 5.
DR   ExpressionAtlas; A0A182DWH7; baseline and differential.
DR   GO; GO:0008430; F:selenium binding; IEA:InterPro.
DR   InterPro; IPR007671; Selenoprotein-P_N.
DR   InterPro; IPR007672; SelP_C.
DR   InterPro; IPR037941; SeP.
DR   PANTHER; PTHR10105; PTHR10105; 1.
DR   Pfam; PF04593; SelP_C; 1.
DR   Pfam; PF04592; SelP_N; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A182DWH7,
KW   ECO:0000213|PeptideAtlas:A0A182DWH7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    310       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5008116504.
FT   DOMAIN       24    247       SelP_N. {ECO:0000259|Pfam:PF04592}.
FT   DOMAIN      251    310       SelP_C. {ECO:0000259|Pfam:PF04593}.
FT   NON_TER     310    310       {ECO:0000313|Ensembl:ENSP00000421626}.
SQ   SEQUENCE   310 AA;  35116 MW;  D4133B1671F37AF2 CRC64;
     MWRSLGLALA LCLLPSGGTE SQDQSSLCKQ PPAWSIRDQD PMLNSNGSVT VVALLQASCY
     LCILQASKLE DLRVKLKKEG YSNISYIVVN HQGISSRLKY THLKNKVSEH IPVYQQEENQ
     TDVWTLLNGS KDDFLIYDRC GRLVYHLGLP FSFLTFPYVE EAIKIAYCEK KCGNCSLTTL
     KDEDFCKRVS LATVDKTVET PSPHYHHEHH HNHGHQHLGS SELSENQQPG APNAPTHPAP
     PGLHHHHKHK GQHRQGHPEN RDMPASEDLQ DLQKKLCRKR CINQLLCKLP TDSELAPRSC
     CCHCRHLIFE
//