ID   A0A0U5GHD6_HUMAN        Unreviewed;       455 AA.
AC   A0A0U5GHD6; A0A0C4ZLV9;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   18-JUL-2018, entry version 15.
DE   SubName: Full=KIR3DL2 {ECO:0000313|EMBL:CEI24340.1};
DE   SubName: Full=Killer cell immunoglobulin-like receptor three domains long cytoplasmic tail 2 {ECO:0000313|EMBL:AJI81047.3};
GN   Name=KIR3DL2 {ECO:0000313|EMBL:CEI24340.1,
GN   ECO:0000313|Ensembl:ENSP00000491738};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:CEI24340.1};
RN   [1] {ECO:0000313|Ensembl:ENSP00000491738, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|EMBL:CEI24340.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=27486779; DOI=10.1016/j.ajhg.2016.06.023;
RA   Norman P.J., Hollenbach J.A., Nemat-Gorgani N., Marin W.M.,
RA   Norberg S.J., Ashouri E., Jayaraman J., Wroblewski E.E., Trowsdale J.,
RA   Rajalingam R., Oksenberg J.R., Chiaroni J., Guethlein L.A.,
RA   Traherne J.A., Ronaghi M., Parham P.;
RT   "Defining KIR and HLA Class I Genotypes at Highest Resolution via
RT   High-Throughput Sequencing.";
RL   Am. J. Hum. Genet. 99:375-391(2016).
RN   [3] {ECO:0000313|EMBL:AJI81047.3}
RP   NUCLEOTIDE SEQUENCE.
RA   Roe D., Vierra-Green C., Pyo C.-W., Eng K., Hall R., Spellman S.,
RA   Ranade S., Geraghty D.E., Maiers M.;
RT   "Full Haplotype Sequences of the Killer Immunoglobulin-like Receptor
RT   (KIR) Region in Several Diverse Diploid Individuals using Single
RT   Molecule, Real-Time Sequencing.";
RL   Submitted (MAY-2016) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|Ensembl:ENSP00000491738}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
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DR   EMBL; KP420442; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KJ535501; AIF79800.1; -; Genomic_DNA.
DR   EMBL; KP420446; AJI81047.3; -; Genomic_DNA.
DR   EMBL; LN649156; CEI24340.1; -; Genomic_DNA.
DR   UniGene; Hs.645228; -.
DR   UniGene; Hs.645532; -.
DR   UniGene; Hs.654605; -.
DR   Ensembl; ENST00000638305; ENSP00000491738; ENSG00000284046.
DR   Ensembl; ENST00000640913; ENSP00000492219; ENSG00000284192.
DR   HGNC; HGNC:6339; KIR3DL2.
DR   eggNOG; ENOG410JAMM; Eukaryota.
DR   eggNOG; ENOG410ZT7K; LUCA.
DR   Proteomes; UP000005640; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 3.
DR   SMART; SM00409; IG; 3.
DR   SUPFAM; SSF48726; SSF48726; 3.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0U5GHD6,
KW   ECO:0000213|PeptideAtlas:A0A0U5GHD6};
KW   Receptor {ECO:0000313|EMBL:AIF79800.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    455       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014038363.
FT   TRANSMEM    339    361       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    118       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      129    209       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      229    316       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   455 AA;  50216 MW;  963AF6FE7F3DBEDB CRC64;
     MSLTVVSMAC VGFFLLQGAW PLMGGQDKPF LSARPSTVVP RGGHVALQCH YRRGFNNFML
     YKEDRSHVPI FHGRIFQESF IMGPVTPAHA GTYRCRGSRP HSLTGWSAPS NPLVIMVTGN
     HRKPSLLAHP GPLLKSGETV ILQCWSDVMF EHFFLHRDGI SEDPSRLVGQ IHDGVSKANF
     SIGPLMPVLA GTYRCYGSVP HSPYQLSAPS DPLDIVITGL YEKPSLSAQP GPTVQAGENV
     TLSCSSWSSY DIYHLSREGE AHERRLRAVP KVNRTFQADF PLGPATHGGT YRCFGSFRAL
     PCVWSNSSDP LLVSVTGNPS SSWPSPTEPS SKSGICRHLH VLIGTSVVIF LFILLLFFLL
     YRWCSNKKNA AVMDQEPAGD RTVNRQDSDE QDPQEVTYAQ LDHCVFIQRK ISRPSQRPKT
     PLTDTSVYTE LPNAEPRSKV VSCPRAPQSG LEGVF
//