ID   A0A0U1RQB8_HUMAN        Unreviewed;       309 AA.
AC   A0A0U1RQB8;
DT   17-FEB-2016, integrated into UniProtKB/TrEMBL.
DT   17-FEB-2016, sequence version 1.
DT   05-DEC-2018, entry version 14.
DE   SubName: Full=Putative alpha-1-antitrypsin-related protein {ECO:0000313|Ensembl:ENSP00000486888};
GN   Name=SERPINA2 {ECO:0000313|Ensembl:ENSP00000486888};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000486888};
RN   [1] {ECO:0000313|Ensembl:ENSP00000486888}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000486888}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (DEC-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the serpin family.
CC       {ECO:0000256|RuleBase:RU000411, ECO:0000256|SAAS:SAAS00596534}.
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DR   EMBL; AL117259; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PeptideAtlas; A0A0U1RQB8; -.
DR   Ensembl; ENST00000553483; ENSP00000486888; ENSG00000258597.
DR   HGNC; HGNC:8985; SERPINA2.
DR   OpenTargets; ENSG00000258597; -.
DR   GeneTree; ENSGT00940000154493; -.
DR   OMA; KIHECFQ; -.
DR   ChiTaRS; SERPINA2; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   InterPro; IPR023796; Serpin_dom.
DR   InterPro; IPR000215; Serpin_fam.
DR   InterPro; IPR036186; Serpin_sf.
DR   PANTHER; PTHR11461; PTHR11461; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   SMART; SM00093; SERPIN; 1.
DR   SUPFAM; SSF56574; SSF56574; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:A0A0U1RQB8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    309       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5006714348.
FT   DOMAIN       62    309       SERPIN. {ECO:0000259|SMART:SM00093}.
SQ   SEQUENCE   309 AA;  35248 MW;  D0EDFD28BCCB5AAB CRC64;
     IPFSVSWGVL LLAGLCCLVP SSLVEDPQED AAQKTDTSHH DQGDWEDLAC QKISYNVTDL
     AFDLYKELAD LSQTSNVLVT PTSVAMAFAM LSLGTKADTR TEILEGLNVN LTETPEAKIH
     ECFQQVLQAL SRPDTRLQLT TGSSLFVNKS MKLVDTFLED TKKLYHSEAS SINFRDTEEA
     KEQINNYVEK RTGRKVVDLV KHLKKDTSLA LVDYISFHGK WKDKFKAERI MVEGFHVDDK
     TIIRVPMINH LGRFDIHRDR ELSSWVLAQH YVGNATAFFI LPDPKKMWQL EEKLTYSHLE
     NIQRAFDIR
//