ID   A0A0G2JR68_HUMAN        Unreviewed;       308 AA.
AC   A0A0G2JR68;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   16-JAN-2019, entry version 23.
DE   SubName: Full=MLX-interacting protein {ECO:0000313|Ensembl:ENSP00000486484};
DE   Flags: Fragment;
GN   Name=MLXIP {ECO:0000313|Ensembl:ENSP00000486484};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000486484, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000213|PubMed:19413330}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=19413330; DOI=10.1021/ac9004309;
RA   Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,
RA   Mohammed S.;
RT   "Lys-N and trypsin cover complementary parts of the phosphoproteome in
RT   a refined SCX-based approach.";
RL   Anal. Chem. 81:4493-4501(2009).
RN   [3] {ECO:0000213|PubMed:23186163}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=23186163;
RA   Zhou H., Di Palma S., Preisinger C., Peng M., Polat A.N., Heck A.J.,
RA   Mohammed S.;
RT   "Toward a comprehensive characterization of a human cancer cell
RT   phosphoproteome.";
RL   J. Proteome Res. 12:260-271(2013).
RN   [4] {ECO:0000313|Ensembl:ENSP00000486484}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; ABBA01020202; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; ABBA01060482; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC130894; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC156455; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC190384; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC205581; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AUXG01000113; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A0G2JR68; -.
DR   jPOST; A0A0G2JR68; -.
DR   PeptideAtlas; A0A0G2JR68; -.
DR   Ensembl; ENST00000626863; ENSP00000486484; ENSG00000281178.
DR   HGNC; HGNC:17055; MLXIP.
DR   ChiTaRS; MLXIP; human.
DR   Proteomes; UP000005640; Unplaced.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:1900402; P:regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter; IEA:InterPro.
DR   CDD; cd00083; HLH; 1.
DR   Gene3D; 4.10.280.10; -; 1.
DR   InterPro; IPR011598; bHLH_dom.
DR   InterPro; IPR036638; HLH_DNA-bd_sf.
DR   InterPro; IPR032648; MLXIP.
DR   PANTHER; PTHR15741:SF23; PTHR15741:SF23; 1.
DR   Pfam; PF00010; HLH; 1.
DR   SMART; SM00353; HLH; 1.
DR   SUPFAM; SSF47459; SSF47459; 1.
DR   PROSITE; PS50888; BHLH; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0G2JR68,
KW   ECO:0000213|PeptideAtlas:A0A0G2JR68};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    308       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002546231.
FT   DOMAIN      190    240       BHLH. {ECO:0000259|PROSITE:PS50888}.
FT   COILED      237    271       {ECO:0000256|SAM:Coils}.
FT   NON_TER     308    308       {ECO:0000313|Ensembl:ENSP00000486484}.
SQ   SEQUENCE   308 AA;  33258 MW;  B57BD97A6F4CDA7A CRC64;
     MVLGALVALS SCPLGLRTSC LTGREAASAG WARPCGPGLH LNILLILAAA FSGQPQAVIM
     TSGPLKREGM LASTVSQSNV VIAPAAIARA PGVPEFHSSI LVTDLGHGTS SPPAPVSRLF
     PSTAQDPLGK GEQVPLHGGS PQVTVTGPSR DCPNSGQASP CASEQSPSPQ SPQNNCSGKS
     DPKNVAALKN RQMKHISAEQ KRRFNIKMCF DMLNSLISNN SKLTSHAITL QKTVEYITKL
     QQERGQMQEE ARRLREEIEE LNATIISCQQ LLPATGVPVT RRQFDHMKDM FDEYVKTRTL
     QNWKFWIV
//