ID   A0A0G2JPA8_HUMAN        Unreviewed;       427 AA.
AC   A0A0G2JPA8;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   16-JAN-2019, entry version 14.
DE   SubName: Full=Alpha-2-antiplasmin {ECO:0000313|Ensembl:ENSP00000483294};
GN   Name=SERPINF2 {ECO:0000313|Ensembl:ENSP00000483294};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000483294, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000483294, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16625196; DOI=10.1038/nature04689;
RA   Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R.,
RA   Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A.,
RA   Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J.,
RA   Chang J.L., Chen C.K., Cook A., Corum B., Cuomo C.A., de Jong P.J.,
RA   DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R.,
RA   Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N.,
RA   Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B.,
RA   Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J.,
RA   Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E.,
RA   Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J.,
RA   Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C.,
RA   Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D.,
RA   Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A.,
RA   Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.;
RT   "DNA sequence of human chromosome 17 and analysis of rearrangement in
RT   the human lineage.";
RL   Nature 440:1045-1049(2006).
RN   [2] {ECO:0000313|Ensembl:ENSP00000483294}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the serpin family.
CC       {ECO:0000256|RuleBase:RU000411, ECO:0000256|SAAS:SAAS00596534}.
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DR   EMBL; AC130343; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC206360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A0G2JPA8; -.
DR   jPOST; A0A0G2JPA8; -.
DR   PeptideAtlas; A0A0G2JPA8; -.
DR   Ensembl; ENST00000615103; ENSP00000483294; ENSG00000276838.
DR   HGNC; HGNC:9075; SERPINF2.
DR   ChiTaRS; SERPINF2; human.
DR   Proteomes; UP000005640; Chromosome 17.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR   GO; GO:0051918; P:negative regulation of fibrinolysis; IEA:InterPro.
DR   CDD; cd02053; alpha2AP; 1.
DR   InterPro; IPR033833; Alpha2AP.
DR   InterPro; IPR023795; Serpin_CS.
DR   InterPro; IPR023796; Serpin_dom.
DR   InterPro; IPR000215; Serpin_fam.
DR   InterPro; IPR036186; Serpin_sf.
DR   PANTHER; PTHR11461; PTHR11461; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   SMART; SM00093; SERPIN; 1.
DR   SUPFAM; SSF56574; SSF56574; 1.
DR   PROSITE; PS00284; SERPIN; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0G2JPA8,
KW   ECO:0000213|PeptideAtlas:A0A0G2JPA8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     27       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        28    427       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002546778.
FT   DOMAIN       44    372       SERPIN. {ECO:0000259|SMART:SM00093}.
SQ   SEQUENCE   427 AA;  47937 MW;  6876B52CA522840B CRC64;
     MALLWGLLVL SWSCLQGPCS VFSPVSAMEP LGWQLTSGPN QEQVSPLTLL KLGNQVQPGA
     QNHTLQRLQQ VLHAGSGPCL PHLLSRLCQD LGPGAFRLAA RMYLQKGFPI KEDFLEQSEQ
     LFGAKPVSLT GKQEDDLANI NQWVKEATEG KIQEFLSGLP EDTVLLLLNA IHFQGFWRNK
     FDPSLTQRDS FHLDEQFTVP VEMMQARTYP LRWFLLEQPE IQVAHFPFKN NMSFVVLVPT
     HFEWNVSQVL ANLSWDTLHP PLVWERPTKV RLPKLYLKHQ MDLVATLSQL GLQELFQAPD
     LRGISEQSLV VSGVQHQSTL ELSEVGVEAA AATSIAMSRM SLSSFSVNRP FLFFIFEDTT
     GLPLFVGSVR NPNPSAPREL KEQQDSPGNK DFLQSLKGFP RGDKLFGPDL KLVPPMEEDY
     PQFGSPK
//