ID   A0A0G2JNE7_HUMAN        Unreviewed;       498 AA.
AC   A0A0G2JNE7;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   16-JAN-2019, entry version 16.
DE   SubName: Full=Leukocyte immunoglobulin-like receptor subfamily B member 2 {ECO:0000313|Ensembl:ENSP00000481228};
GN   Name=LILRB2 {ECO:0000313|Ensembl:ENSP00000481228};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000481228, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000481228, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000481228}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC010518; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A0G2JNE7; -.
DR   jPOST; A0A0G2JNE7; -.
DR   PeptideAtlas; A0A0G2JNE7; -.
DR   Ensembl; ENST00000621522; ENSP00000481228; ENSG00000275463.
DR   HGNC; HGNC:6606; LILRB2.
DR   ChiTaRS; LILRB2; human.
DR   Proteomes; UP000005640; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 4.
DR   InterPro; IPR016332; A1B_glyco/leuk_Ig-like_rcpt.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   Pfam; PF13895; Ig_2; 1.
DR   PIRSF; PIRSF001979; Alpha_1B_glycoprot_prd; 1.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 3.
DR   SUPFAM; SSF48726; SSF48726; 4.
DR   PROSITE; PS50835; IG_LIKE; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|PIRSR:PIRSR001979-1};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0G2JNE7,
KW   ECO:0000213|PeptideAtlas:A0A0G2JNE7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    498       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002546115.
FT   TRANSMEM    447    471       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       15     98       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      213    302       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DISULFID     37     86       {ECO:0000256|PIRSR:PIRSR001979-1}.
FT   DISULFID    132    184       {ECO:0000256|PIRSR:PIRSR001979-1}.
SQ   SEQUENCE   498 AA;  54211 MW;  D3B1B0E61201D4C2 CRC64;
     MTPIVTVLIC LGTIPKPTLW AEPDSVITQG SPVTLSCQGS LEAQEYRLYR EKKSASWITR
     IRPELVKNGQ FHIPSITWEH TGRYGCQYYS RARWSELSDP LVLVMTGAYP KPTLSAQPSP
     VVTSGGRVTL QCESQVAFGG FILCKEGEEE HPQCLNSQPH ARGSSRAIFS VGPVSPNRRW
     SHRCYGYDLN SPYVWSSPSD LLELLVPGVS KKPSLSVQPG PVVAPGESLT LQCVSDVGYD
     RFVLYKEGER DLRQLPGRQP QAGLSQANFT LGPVSRSYGG QYRCYGAHNL SSECSAPSDP
     LDILITGQIR GTPFISVQPG PTVASGENVT LLCQSWRQFH TFLLTKAGAA DAPLRLRSIH
     EYPKYQAEFP MSPVTSAHAG TYRCYGSLNS DPYLLSHPSE PLELVVSGPS MGSSPPPTGP
     ISTPAGPEDQ PLTPTGSDPQ SGLGRHLGVV IGILVAVVLL LLLLLLLFLI LRHRRQGKHW
     TSSPAQLPTP RKKTSMLP
//