ID   A0A0G2JNE3_HUMAN        Unreviewed;       398 AA.
AC   A0A0G2JNE3;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   16-JAN-2019, entry version 15.
DE   SubName: Full=Killer cell immunoglobulin-like receptor 2DS4 {ECO:0000313|Ensembl:ENSP00000481214};
GN   Name=KIR2DS4 {ECO:0000313|Ensembl:ENSP00000481214};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000481214, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000481214, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000481214}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
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DR   EMBL; GU182342; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A0G2JNE3; -.
DR   PeptideAtlas; A0A0G2JNE3; -.
DR   Ensembl; ENST00000617783; ENSP00000481214; ENSG00000273526.
DR   HGNC; HGNC:6336; KIR2DS4.
DR   Proteomes; UP000005640; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 3.
DR   SMART; SM00409; IG; 3.
DR   SUPFAM; SSF48726; SSF48726; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    398       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002546314.
FT   TRANSMEM    338    359       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       35    117       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      128    208       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      228    315       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   398 AA;  43927 MW;  70918A17C10BD483 CRC64;
     MSLMVIIMAC VGFFLLQGAW PQEGGQDKPL LSTWPSLVVP PEHVTLQCHS NLGFNNFSLY
     KDDGVPVPEL YNRIFWKSLF MGPVTPSHAG TYRCRGSHTH SPSGWSAPSN PLVIMVTGVH
     RKPSFLALPG HLVKSEETVI LQCWSDVMFE HFLLHREGKF NNTLHLIGEH HDGVSKANFS
     IGPMMPVLAG TYRCYGSVPH SPYQLSAPSD PLDMVIIGLY EKPSLSAQPG PTVQAGENVT
     LSCSSRSSYD MYHLSREGEA HERRLPAVRS INGTFQADFP LGPATHGGTY RCFGSFRDAP
     YEWSNSSDPL LVSVTGNPSN SWPSPTEPSS KTGNPRHLHV LIGTSVVKIP FTILLFFLLH
     RWCSDKKNAA VMDQEPAGNR TVNSEDSDEQ DHQEVSYA
//