ID   A0A0G2JN05_HUMAN        Unreviewed;       287 AA.
AC   A0A0G2JN05;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   16-JAN-2019, entry version 22.
DE   SubName: Full=Killer cell immunoglobulin-like receptor 2DL5A {ECO:0000313|Ensembl:ENSP00000492490};
DE   SubName: Full=Killer cell immunoglobulin-like receptor 2DL5B {ECO:0000313|Ensembl:ENSP00000491446};
DE   SubName: Full=Killer cell immunoglobulin-like receptor 3DS1 {ECO:0000313|Ensembl:ENSP00000480346};
GN   Name=KIR2DL5B {ECO:0000313|Ensembl:ENSP00000491446};
GN   Synonyms=KIR2DL5A {ECO:0000313|Ensembl:ENSP00000492490},
GN   KIR3DS1 {ECO:0000313|Ensembl:ENSP00000480346};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000480346, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000480346, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000480346}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000491446}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
RN   [4] {ECO:0000313|Ensembl:ENSP00000494005}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2018) to UniProtKB.
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DR   EMBL; GU182347; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KP420440; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KU645196; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KU645197; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001269099.1; NM_001282170.1.
DR   UniGene; Hs.743496; -.
DR   ProteinModelPortal; A0A0G2JN05; -.
DR   jPOST; A0A0G2JN05; -.
DR   Ensembl; ENST00000620731; ENSP00000480346; ENSG00000275037.
DR   Ensembl; ENST00000638609; ENSP00000492490; ENSG00000283889.
DR   Ensembl; ENST00000639497; ENSP00000491787; ENSG00000284111.
DR   Ensembl; ENST00000639696; ENSP00000492735; ENSG00000283719.
DR   Ensembl; ENST00000639892; ENSP00000491446; ENSG00000284301.
DR   Ensembl; ENST00000642388; ENSP00000494356; ENSG00000283719.
DR   Ensembl; ENST00000642472; ENSP00000494005; ENSG00000283889.
DR   Ensembl; ENST00000643091; ENSP00000494548; ENSG00000284301.
DR   Ensembl; ENST00000645896; ENSP00000496009; ENSG00000284111.
DR   GeneID; 3813; -.
DR   CTD; 3813; -.
DR   HGNC; HGNC:16345; KIR2DL5A.
DR   HGNC; HGNC:16346; KIR2DL5B.
DR   HGNC; HGNC:6340; KIR3DS1.
DR   OrthoDB; 466470at2759; -.
DR   GenomeRNAi; 3813; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 2.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; SSF48726; 2.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    287       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5015039218.
FT   TRANSMEM    244    265       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    114       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      134    221       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   287 AA;  31764 MW;  C2B7C487FF4117BF CRC64;
     MLLMVVSMAC VGLFLVQRAG PHMGNHRKPS LLAHPGPLVK SGERVILQCW SDIMFEHFFL
     HKEWISKDPS RLVGQIHDGV SKANFSIGSM MRALAGTYRC YGSVTHTPYQ LSAPSDPLDI
     VVTGLYEKPS LSAQPGPKVQ AGESVTLSCS SRSSYDMYHL SREGGAHERR LPAVRKVNRT
     FQADFPLGPA THGGTYRCFG SFRHSPYEWS DPSDPLLVSV TGNPSSSWPS PTEPSSKSGN
     LRHLHILIGT SVVKIPFTIL LFFLLHRWCS NKKKCCCNGP RACREQK
//