ID   A0A0G2JMW3_HUMAN        Unreviewed;       845 AA.
AC   A0A0G2JMW3;
DT   22-JUL-2015, integrated into UniProtKB/TrEMBL.
DT   22-JUL-2015, sequence version 1.
DT   16-JAN-2019, entry version 23.
DE   SubName: Full=Cadherin-related family member 5 {ECO:0000313|Ensembl:ENSP00000480151};
GN   Name=CDHR5 {ECO:0000313|Ensembl:ENSP00000480151};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000480151, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000480151, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
RN   [3] {ECO:0000313|Ensembl:ENSP00000480151}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
RN   [4] {ECO:0000313|Ensembl:ENSP00000488376}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2015) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC138374; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   jPOST; A0A0G2JMW3; -.
DR   PeptideAtlas; A0A0G2JMW3; -.
DR   Ensembl; ENST00000617105; ENSP00000480151; ENSG00000273572.
DR   Ensembl; ENST00000633633; ENSP00000488376; ENSG00000273572.
DR   HGNC; HGNC:7521; CDHR5.
DR   ChiTaRS; CDHR5; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR030326; Mucdhl.
DR   PANTHER; PTHR45160; PTHR45160; 1.
DR   SMART; SM00112; CA; 3.
DR   SUPFAM; SSF49313; SSF49313; 4.
DR   PROSITE; PS00232; CADHERIN_1; 1.
PE   1: Evidence at protein level;
KW   Calcium {ECO:0000256|SAAS:SAAS00020193};
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAAS:SAAS00616217, ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0G2JMW3,
KW   ECO:0000213|PeptideAtlas:A0A0G2JMW3};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Repeat {ECO:0000256|SAAS:SAAS00436611};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS00616217,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00616217,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    845       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014024469.
FT   TRANSMEM    668    690       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       29    122       CA. {ECO:0000259|SMART:SM00112}.
FT   DOMAIN      149    235       CA. {ECO:0000259|SMART:SM00112}.
FT   DOMAIN      274    352       CA. {ECO:0000259|SMART:SM00112}.
SQ   SEQUENCE   845 AA;  88128 MW;  39F6527022F30008 CRC64;
     MGSWALLWPP LLFTGLLVRP PGTMAQAQYC SVNKDIFEVE ENTNVTEPLV DIHVPEGQEV
     TLGALSTPFA FRIQGNQLFL NVTPDYEEKS LLEAQLLCQS GGTLVTQLRV FVSVLDVNDN
     APEFPFKTKE IRVEEDTKVN STVIPETQLQ AEDRDKDDIL FYTLQEMTAG ASDYFSLVSV
     NRPALRLDRP LDFYERPNMT FWLLVRDTPG ENVEPSHTAT ATLVLNVVPA DLRPPWFLPC
     TFSDGYVCIQ AQYHGAVPTG HILPSPLVLR PGPIYAEDGD RGINQPIIYS IFRGNVNGTF
     IIHPDSGNLT VARSVPSPMT FLLLVKGQQA DLARYSVTQV TVEAVAAAGS PPRFPQSLYR
     GTVARGAGAG VVVKDAAAPS QPLRIQAQDP EFSDLNSAIT YRITNHSHFR MEGEVVLTTT
     TLAQAGAFYA EVEAHNTVTS GTATTVIEIQ VSEQEPPSTD VPPSPEAGGT TGPWTSTTSE
     VPRPPEPSQG PSTTSSGGGT GPHPPSGTTL RPPTSSTPGG SPGAENSTSH QPATPGGDTA
     QTPKPGTSQP MPPGVGTSTS HQPATPSGGT AQTPEPGTSQ PMPPSMGTST SHQPATPGGG
     TAQTPEAGTS QPMPPGMGTS TSHQPTTPGG GTAQTPEPGT SQPMPLSKST PSSGGGPSED
     KRFSVVDMAA LGGVLGALLL LALLGLAVLV HKHYGPRLKC CSGKAPEPQP QGFDNQAFLP
     DHKANWAPVP SPTHDPKPAE APMPAEPAPP GPASPGGAPE PPAAARAGGS PTAVRSILTK
     ERRPEGGYKA VWFGEDIGTE ADVVVLNAPT LDVDGASDSG SGDEGEGAGR GGGPYDAPGG
     DDSYI
//