ID   A0A0C4DH35_HUMAN        Unreviewed;       117 AA.
AC   A0A0C4DH35;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   13-FEB-2019, entry version 32.
DE   SubName: Full=Immunoglobulin heavy variable 3-35 (non-functional) {ECO:0000313|Ensembl:ENSP00000375026};
DE   Flags: Fragment;
GN   Name=IGHV3-35 {ECO:0000313|Ensembl:ENSP00000375026};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000375026, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000375026, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000375026}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2015) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000488667}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (AUG-2015) to UniProtKB.
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DR   EMBL; AC245166; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; A0A0C4DH35; -.
DR   BioMuta; IGHV3-35; -.
DR   jPOST; A0A0C4DH35; -.
DR   PeptideAtlas; A0A0C4DH35; -.
DR   Ensembl; ENST00000390617; ENSP00000375026; ENSG00000211957.
DR   Ensembl; ENST00000632225; ENSP00000488667; ENSG00000282104.
DR   EuPathDB; HostDB:ENSG00000211957.2; -.
DR   GeneCards; IGHV3-35; -.
DR   HGNC; HGNC:5598; IGHV3-35.
DR   OpenTargets; ENSG00000211957; -.
DR   GeneTree; ENSGT00940000164192; -.
DR   OMA; CARESQR; -.
DR   ChiTaRS; IGHV3-35; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000211957; Expressed in 62 organ(s), highest expression level in lymph node.
DR   GO; GO:0009897; C:external side of plasma membrane; IBA:GO_Central.
DR   GO; GO:0042571; C:immunoglobulin complex, circulating; IBA:GO_Central.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0034987; F:immunoglobulin receptor binding; IBA:GO_Central.
DR   GO; GO:0050853; P:B cell receptor signaling pathway; IBA:GO_Central.
DR   GO; GO:0006958; P:complement activation, classical pathway; IBA:GO_Central.
DR   GO; GO:0042742; P:defense response to bacterium; IBA:GO_Central.
DR   GO; GO:0045087; P:innate immune response; IBA:GO_Central.
DR   GO; GO:0006911; P:phagocytosis, engulfment; IBA:GO_Central.
DR   GO; GO:0006910; P:phagocytosis, recognition; IBA:GO_Central.
DR   GO; GO:0050871; P:positive regulation of B cell activation; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR013106; Ig_V-set.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00406; IGv; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0C4DH35,
KW   ECO:0000213|PeptideAtlas:A0A0C4DH35};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    117       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014019438.
FT   DOMAIN       31    117       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER     117    117       {ECO:0000313|Ensembl:ENSP00000375026}.
SQ   SEQUENCE   117 AA;  12810 MW;  5202AF4149E92BDB CRC64;
     MEFGLSWVFL AAILKGVQCE VQLVESGGGL VQPGGSLRLS CAASGFTFSN SDMNWVHQAP
     GKGLEWVSGV SWNGSRTHYA DSVKGRFIIS RDNSRNTLYL QTNSLRAEDT AVYYCVR
//