ID   A0A0C4DGK4_HUMAN        Unreviewed;       398 AA.
AC   A0A0C4DGK4;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   16-JAN-2019, entry version 29.
DE   SubName: Full=Neurexin-3-beta {ECO:0000313|Ensembl:ENSP00000451393};
GN   Name=NRXN3 {ECO:0000313|Ensembl:ENSP00000451393};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000451393, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000451393, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12508121; DOI=10.1038/nature01348;
RA   Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C.,
RA   Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A.,
RA   Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S.,
RA   Sun H., Du H., Pepin K., Artiguenave F., Robert C., Cruaud C.,
RA   Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P.,
RA   Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N.,
RA   Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C.,
RA   Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S.,
RA   Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B.,
RA   Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M.,
RA   Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S.,
RA   Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D.,
RA   Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A.,
RA   Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M.,
RA   Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V.,
RA   Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L.,
RA   Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J.,
RA   Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W.,
RA   Quetier F., Waterston R., Hood L., Weissenbach J.;
RT   "The DNA sequence and analysis of human chromosome 14.";
RL   Nature 421:601-607(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000451393}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2015) to UniProtKB.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
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DR   EMBL; AC007056; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC007955; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC008045; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC009396; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC011440; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AF099810; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455954; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455956; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   UniGene; Hs.368307; -.
DR   ProteinModelPortal; A0A0C4DGK4; -.
DR   jPOST; A0A0C4DGK4; -.
DR   PeptideAtlas; A0A0C4DGK4; -.
DR   Ensembl; ENST00000555387; ENSP00000451393; ENSG00000021645.
DR   EuPathDB; HostDB:ENSG00000021645.18; -.
DR   HGNC; HGNC:8010; NRXN3.
DR   OpenTargets; ENSG00000021645; -.
DR   GeneTree; ENSGT00940000154618; -.
DR   ChiTaRS; NRXN3; human.
DR   Proteomes; UP000005640; Chromosome 14.
DR   Bgee; ENSG00000021645; Expressed in 177 organ(s), highest expression level in cerebellar vermis.
DR   ExpressionAtlas; A0A0C4DGK4; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:InterPro.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR001791; Laminin_G.
DR   InterPro; IPR037440; Neurexin.
DR   PANTHER; PTHR44287; PTHR44287; 1.
DR   Pfam; PF02210; Laminin_G_2; 1.
DR   SMART; SM00282; LamG; 1.
DR   SUPFAM; SSF49899; SSF49899; 1.
DR   PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0C4DGK4,
KW   ECO:0000213|PeptideAtlas:A0A0C4DGK4};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     35       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        36    398       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002170050.
FT   DOMAIN       85    285       LAM_G_DOMAIN.
FT                                {ECO:0000259|PROSITE:PS50025}.
SQ   SEQUENCE   398 AA;  43954 MW;  ED70060383F7CCCD CRC64;
     MHLRIHARRS PPRRPAWTLG IWFLFWGCIV SSVWSSSNVA SSSSTSSSPG SHSQHEHHFH
     GSKHHSVPIS IYRSPVSLRG GHAGATYIFG KSGGLILYTW PANDRPSTRS DRLAVGFSTT
     VKDGILVRID SAPGLGDFLQ LHIEQGKIGV VFNIGTVDIS IKEERTPVND GKYHVVRFTR
     NGGNATLQVD NWPVNEHYPT GNTDNERFQM VKQKIPFKYN RPVEEWLQEK GRQLTIFNTQ
     AQIAIGGKDK GRLFQGQLSG LYYDGLKVLN MAAENNPNIK INGSVRLVGE VPSILGTTQT
     TSMPPEMSTT VMETTTTMAT TTTRKNRSTA SIQPTSDDLV SSAECSSDDE DFVECEPSTG
     RSARSSNAAR SLRAALTWTW RLTYTFTPII FISCVVHS
//