ID   A0A0C4DFT7_HUMAN        Unreviewed;       150 AA.
AC   A0A0C4DFT7;
DT   01-APR-2015, integrated into UniProtKB/TrEMBL.
DT   01-APR-2015, sequence version 1.
DT   16-JAN-2019, entry version 28.
DE   RecName: Full=Glycophorin {ECO:0000256|PIRNR:PIRNR002466};
GN   Name=GYPA {ECO:0000313|Ensembl:ENSP00000354003};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000354003, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000354003, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000213|PubMed:24275569}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=24275569; DOI=10.1016/j.jprot.2013.11.014;
RA   Bian Y., Song C., Cheng K., Dong M., Wang F., Huang J., Sun D.,
RA   Wang L., Ye M., Zou H.;
RT   "An enzyme assisted RP-RPLC approach for in-depth analysis of human
RT   liver phosphoproteome.";
RL   J. Proteomics 96:253-262(2014).
RN   [3] {ECO:0000313|Ensembl:ENSP00000354003}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (FEB-2015) to UniProtKB.
RN   [4] {ECO:0000313|Ensembl:ENSP00000493142}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (MAY-2018) to UniProtKB.
CC   -!- INTERACTION:
CC       O43889-2:CREB3; NbExp=3; IntAct=EBI-12044847, EBI-625022;
CC       Q14145:KEAP1; NbExp=3; IntAct=EBI-12044847, EBI-751001;
CC       O43765:SGTA; NbExp=3; IntAct=EBI-12044847, EBI-347996;
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DR   EMBL; AC107223; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_002090.4; NM_002099.7.
DR   UniGene; Hs.434973; -.
DR   ProteinModelPortal; A0A0C4DFT7; -.
DR   SMR; A0A0C4DFT7; -.
DR   IntAct; A0A0C4DFT7; 3.
DR   PRIDE; A0A0C4DFT7; -.
DR   Ensembl; ENST00000360771; ENSP00000354003; ENSG00000170180.
DR   Ensembl; ENST00000641688; ENSP00000493142; ENSG00000170180.
DR   GeneID; 2993; -.
DR   KEGG; hsa:2993; -.
DR   CTD; 2993; -.
DR   EuPathDB; HostDB:ENSG00000170180.19; -.
DR   HGNC; HGNC:4702; GYPA.
DR   OpenTargets; ENSG00000170180; -.
DR   eggNOG; ENOG410JM5B; Eukaryota.
DR   eggNOG; ENOG4111AH6; LUCA.
DR   GeneTree; ENSGT00550000075214; -.
DR   KO; K06575; -.
DR   OMA; THYPPEE; -.
DR   OrthoDB; 1548637at2759; -.
DR   PhylomeDB; A0A0C4DFT7; -.
DR   GenomeRNAi; 2993; -.
DR   Proteomes; UP000005640; Chromosome 4.
DR   Bgee; ENSG00000170180; Expressed in 87 organ(s), highest expression level in trabecular bone tissue.
DR   ExpressionAtlas; A0A0C4DFT7; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR001195; Glycophorin.
DR   InterPro; IPR018938; Glycophorin_CS.
DR   PANTHER; PTHR13813; PTHR13813; 1.
DR   PIRSF; PIRSF002466; Glycophorin; 1.
DR   PROSITE; PS00312; GLYCOPHORIN_A; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Glycoprotein {ECO:0000256|PIRNR:PIRNR002466};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0C4DFT7,
KW   ECO:0000213|PeptideAtlas:A0A0C4DFT7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Sialic acid {ECO:0000256|PIRNR:PIRNR002466};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     19       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        20    150       Glycophorin. {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002181412.
FT   TRANSMEM     92    114       Helical. {ECO:0000256|SAM:Phobius}.
SQ   SEQUENCE   150 AA;  16430 MW;  53664F3D330A98A9 CRC64;
     MYGKIIFVLL LSEIVSISAL STTEVAMHTS TSSSVTKSYI SSQTNDTHKR DTYAATPRAH
     EVSEISVRTV YPPEEETGER VQLAHHFSEP EITLIIFGVM AGVIGTILLI SYGIRRLIKK
     SPSDVKPLPS PDTDVPLSSV EIENPETSDQ
//