ID   A0A0B4J202_HUMAN        Unreviewed;       158 AA.
AC   A0A0B4J202;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   16-JAN-2019, entry version 20.
DE   SubName: Full=Neuromedin-U {ECO:0000313|Ensembl:ENSP00000422399};
GN   Name=NMU {ECO:0000313|Ensembl:ENSP00000422399};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000422399, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000422399, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000422399}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2015) to UniProtKB.
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DR   EMBL; AC024243; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001278974.1; NM_001292045.1.
DR   UniGene; Hs.418367; -.
DR   jPOST; A0A0B4J202; -.
DR   Ensembl; ENST00000511469; ENSP00000422399; ENSG00000109255.
DR   GeneID; 10874; -.
DR   CTD; 10874; -.
DR   EuPathDB; HostDB:ENSG00000109255.11; -.
DR   HGNC; HGNC:7859; NMU.
DR   OpenTargets; ENSG00000109255; -.
DR   GeneTree; ENSGT00510000048726; -.
DR   OrthoDB; 1515830at2759; -.
DR   GenomeRNAi; 10874; -.
DR   Proteomes; UP000005640; Chromosome 4.
DR   Bgee; ENSG00000109255; Expressed in 145 organ(s), highest expression level in mouth mucosa.
DR   ExpressionAtlas; A0A0B4J202; baseline and differential.
DR   GO; GO:0006940; P:regulation of smooth muscle contraction; IEA:InterPro.
DR   InterPro; IPR018070; Neuromedin-U_amidation-site.
DR   InterPro; IPR008200; NMU_C.
DR   Pfam; PF02070; NMU; 1.
DR   SMART; SM00084; NMU; 1.
DR   PROSITE; PS00967; NMU; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0B4J202,
KW   ECO:0000213|PeptideAtlas:A0A0B4J202};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     38       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        39    158       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002105570.
FT   DOMAIN      126    150       NMU. {ECO:0000259|SMART:SM00084}.
SQ   SEQUENCE   158 AA;  18003 MW;  7ADE02A74AD44CB3 CRC64;
     MLRTESCRPR SPAGQVAAAS PLLLLLLLLA WCAGACRGAP ILPQGLQPEQ QLQLWNEASN
     ALEELCFMIM GMLPKPQEQD EKDNTKRFLF HYSKTQKLGK SNVVSSVVHP LLQLVPHLHE
     RRMKRFRVDE EFQSPFASQS RGYFLFRPRN GRRSAGFI
//