ID   A0A0B4J1W8_HUMAN        Unreviewed;       151 AA.
AC   A0A0B4J1W8;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   16-JAN-2019, entry version 25.
DE   SubName: Full=ALK and LTK ligand 2 {ECO:0000313|Ensembl:ENSP00000389939};
DE   Flags: Fragment;
GN   Name=ALKAL2 {ECO:0000313|Ensembl:ENSP00000389939};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000389939, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000389939, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H.,
RA   Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M.,
RA   Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E.,
RA   Kremitzki C., Oddy L., Du H., Sun H., Bradshaw-Cordum H., Ali J.,
RA   Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C.,
RA   Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J.,
RA   Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A.,
RA   Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K.,
RA   Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M.,
RA   Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N.,
RA   Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M.,
RA   Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E.,
RA   Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P.,
RA   Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A.,
RA   Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A.,
RA   Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T.,
RA   Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D.,
RA   Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X.,
RA   McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D.,
RA   Waterston R.H., Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2
RT   and 4.";
RL   Nature 434:724-731(2005).
RN   [2] {ECO:0000313|Ensembl:ENSP00000389939}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2015) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AC079779; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_006711942.1; XM_006711879.3.
DR   UniGene; Hs.355207; -.
DR   ProteinModelPortal; A0A0B4J1W8; -.
DR   PeptideAtlas; A0A0B4J1W8; -.
DR   Ensembl; ENST00000452023; ENSP00000389939; ENSG00000189292.
DR   GeneID; 285016; -.
DR   CTD; 285016; -.
DR   EuPathDB; HostDB:ENSG00000189292.15; -.
DR   HGNC; HGNC:27683; ALKAL2.
DR   OpenTargets; ENSG00000189292; -.
DR   eggNOG; ENOG410IX76; Eukaryota.
DR   eggNOG; ENOG410Y5NM; LUCA.
DR   GeneTree; ENSGT00940000162505; -.
DR   OMA; YHSGESK; -.
DR   OrthoDB; 1432187at2759; -.
DR   GenomeRNAi; 285016; -.
DR   Proteomes; UP000005640; Chromosome 2.
DR   Bgee; ENSG00000189292; Expressed in 158 organ(s), highest expression level in right adrenal gland.
DR   ExpressionAtlas; A0A0B4J1W8; baseline and differential.
DR   GO; GO:0030298; F:receptor signaling protein tyrosine kinase activator activity; IEA:InterPro.
DR   GO; GO:0030971; F:receptor tyrosine kinase binding; IEA:InterPro.
DR   InterPro; IPR029364; FAM150A/B.
DR   PANTHER; PTHR28676; PTHR28676; 1.
DR   Pfam; PF15129; FAM150; 1.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0B4J1W8,
KW   ECO:0000213|PeptideAtlas:A0A0B4J1W8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     24       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        25    151       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002091818.
FT   NON_TER     151    151       {ECO:0000313|Ensembl:ENSP00000389939}.
SQ   SEQUENCE   151 AA;  16787 MW;  9047F0FFA23D013B CRC64;
     MRGPGHPLLL GLLLVLGAAG RGRGGAEPRE PADGQALLRL VVELVQELRK HHSAEHKGLQ
     LLGRDCALGR AEAAGLGPSP EQRVEIVPRD LRMKDKFLKH LTGPLYFSPK CSKHFHRLYH
     NTRDCTIPAY YKRCARLLTR LAVSPVCMED K
//