ID   A0A0B4J1W1_HUMAN        Unreviewed;       650 AA.
AC   A0A0B4J1W1;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   16-JAN-2019, entry version 31.
DE   SubName: Full=Leukocyte immunoglobulin-like receptor subfamily B member 1 {ECO:0000313|Ensembl:ENSP00000379622};
GN   Name=LILRB1 {ECO:0000313|Ensembl:ENSP00000379622};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000379622, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000379622, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000379622}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2015) to UniProtKB.
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DR   EMBL; AC245036; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_006660.4; NM_006669.6.
DR   RefSeq; XP_016881674.1; XM_017026185.1.
DR   UniGene; Hs.667388; -.
DR   SMR; A0A0B4J1W1; -.
DR   jPOST; A0A0B4J1W1; -.
DR   PeptideAtlas; A0A0B4J1W1; -.
DR   PRIDE; A0A0B4J1W1; -.
DR   Ensembl; ENST00000396331; ENSP00000379622; ENSG00000104972.
DR   GeneID; 10859; -.
DR   KEGG; hsa:10859; -.
DR   CTD; 10859; -.
DR   EuPathDB; HostDB:ENSG00000104972.15; -.
DR   HGNC; HGNC:6605; LILRB1.
DR   OpenTargets; ENSG00000104972; -.
DR   eggNOG; ENOG410IKJD; Eukaryota.
DR   eggNOG; ENOG41116BR; LUCA.
DR   GeneTree; ENSGT00940000153160; -.
DR   KO; K06512; -.
DR   OrthoDB; 1000446at2759; -.
DR   ChiTaRS; LILRB1; human.
DR   GenomeRNAi; 10859; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000104972; Expressed in 179 organ(s), highest expression level in spleen.
DR   ExpressionAtlas; A0A0B4J1W1; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 4.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 1.
DR   Pfam; PF13895; Ig_2; 1.
DR   SMART; SM00409; IG; 4.
DR   SMART; SM00408; IGc2; 3.
DR   SUPFAM; SSF48726; SSF48726; 4.
DR   PROSITE; PS50835; IG_LIKE; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0B4J1W1,
KW   ECO:0000213|PeptideAtlas:A0A0B4J1W1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    650       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002105561.
FT   TRANSMEM    459    483       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       27    115       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      313    409       Ig-like. {ECO:0000259|PROSITE:PS50835}.
SQ   SEQUENCE   650 AA;  70847 MW;  D5924C5782B386BB CRC64;
     MTPILTVLIC LGLSLGPRTH VQAGHLPKPT LWAEPGSVIT QGSPVTLRCQ GGQETQEYRL
     YREKKTAPWI TRIPQELVKK GQFPIPSITW EHTGRYRCYY GSDTAGRSES SDPLELVVTG
     AYIKPTLSAQ PSPVVNSGGN VTLQCDSQVA FDGFILCKEG EDEHPQCLNS QPHARGSSRA
     IFSVGPVSPS RRWWYRCYAY DSNSPYEWSL PSDLLELLVL GVSKKPSLSV QPGPIVAPEE
     TLTLQCGSDA GYNRFVLYKD GERDFLQLAG AQPQAGLSQA NFTLGPVSRS YGGQYRCYGA
     HNLSSEWSAP SDPLDILIAG QFYDRVSLSV QPGPTVASGE NVTLLCQSQG WMQTFLLTKE
     GAADDPWRLR STYQSQKYQA EFPMGPVTSA HAGTYRCYGS QSSKPYLLTH PSDPLELVVS
     GPSGGPSSPT TGPTSTSGPE DQPLTPTGSD PQSGLGRHLG VVIGILVAVI LLLLLLLLLF
     LILRHRRQGK HWTSTQRKAD FQHPAGAVGP EPTDRGLQWR SSPAADAQEE NLYAAVKHTQ
     PEDGVEMDTR SPHDEDPQAV TYAEVKHSRP RREMASPPSP LSGEFLDTKD RQAEEDRQMD
     TEAAASEAPQ DVTYAQLHSL TLRREATEPP PSQEGPSPAV PSIYATLAIH
//