ID   A0A0B4J1R5_HUMAN        Unreviewed;       410 AA.
AC   A0A0B4J1R5;
DT   04-MAR-2015, integrated into UniProtKB/TrEMBL.
DT   04-MAR-2015, sequence version 1.
DT   16-JAN-2019, entry version 28.
DE   SubName: Full=Killer cell immunoglobulin-like receptor 3DL3 {ECO:0000313|Ensembl:ENSP00000291860};
GN   Name=KIR3DL3 {ECO:0000313|Ensembl:ENSP00000291860};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000291860, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000291860, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000291860}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2015) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000484725}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2015) to UniProtKB.
RN   [4] {ECO:0000313|Ensembl:ENSP00000492021}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
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DR   EMBL; AC245128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KU842452; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_703144.3; NM_153443.4.
DR   UniGene; Hs.645224; -.
DR   jPOST; A0A0B4J1R5; -.
DR   PeptideAtlas; A0A0B4J1R5; -.
DR   PRIDE; A0A0B4J1R5; -.
DR   Ensembl; ENST00000291860; ENSP00000291860; ENSG00000242019.
DR   Ensembl; ENST00000614255; ENSP00000484725; ENSG00000276930.
DR   Ensembl; ENST00000640839; ENSP00000492021; ENSG00000283875.
DR   GeneID; 115653; -.
DR   KEGG; hsa:115653; -.
DR   CTD; 115653; -.
DR   EuPathDB; HostDB:ENSG00000242019.1; -.
DR   HGNC; HGNC:16312; KIR3DL3.
DR   OpenTargets; ENSG00000242019; -.
DR   eggNOG; ENOG410JAMM; Eukaryota.
DR   eggNOG; ENOG410ZT7K; LUCA.
DR   GeneTree; ENSGT00940000153748; -.
DR   KO; K07980; -.
DR   OMA; LYNRIFR; -.
DR   OrthoDB; 1055520at2759; -.
DR   ChiTaRS; KIR3DL3; human.
DR   GenomeRNAi; 115653; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000242019; Expressed in 11 organ(s), highest expression level in amniotic fluid.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013151; Immunoglobulin.
DR   Pfam; PF00047; ig; 2.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 1.
DR   SUPFAM; SSF48726; SSF48726; 3.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Immunoglobulin domain {ECO:0000256|SAAS:SAAS00442402};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     25       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        26    410       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014018839.
FT   TRANSMEM    322    343       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    118       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN       40    102       IGc2. {ECO:0000259|SMART:SM00408}.
FT   DOMAIN      129    218       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      229    325       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   410 AA;  44905 MW;  D1C2B66B8898F538 CRC64;
     MSLMVVSMAC VGFFLLEGPW PHVGGQDKPF LSAWPGTVVS EGQHVTLQCR SRLGFNEFSL
     SKEDGMPVPE LYNRIFRNSF LMGPVTPAHA GTYRCCSSHP HSPTGWSAPS NPVVIMVTGV
     HRKPSLLAHP GPLVKSGETV ILQCWSDVRF ERFLLHREGI TEDPLRLVGQ LHDAGSQVNY
     SMGPMTPALA GTYRCFGSVT HLPYELSAPS DPLDIVVVGL YGKPSLSAQP GPTVQAGENV
     TLSCSSRSLF DIYHLSREAE AGELRLTAVL RVNGTFQANF PLGPVTHGGN YRCFGSFRAL
     PHAWSDPSDP LPVSVTGNSR NLHVLIGTSV VIIPFAILLF FLLHRWCANK KNAVVMDQEP
     AGNRTVNRED SDEQDPQEVT YAQLNHCVFT QRKITRPSQR PKTPPTDTSV
//