ID   A0A0A0MTU0_HUMAN        Unreviewed;       303 AA.
AC   A0A0A0MTU0;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-JAN-2019, entry version 29.
DE   SubName: Full=Natural cytotoxicity triggering receptor 1 {ECO:0000313|Ensembl:ENSP00000471986};
GN   Name=NCR1 {ECO:0000313|Ensembl:ENSP00000471986};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000471986, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000471986, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15057824; DOI=10.1038/nature02399;
RA   Grimwood J., Gordon L.A., Olsen A.S., Terry A., Schmutz J.,
RA   Lamerdin J.E., Hellsten U., Goodstein D., Couronne O., Tran-Gyamfi M.,
RA   Aerts A., Altherr M., Ashworth L., Bajorek E., Black S., Branscomb E.,
RA   Caenepeel S., Carrano A.V., Caoile C., Chan Y.M., Christensen M.,
RA   Cleland C.A., Copeland A., Dalin E., Dehal P., Denys M., Detter J.C.,
RA   Escobar J., Flowers D., Fotopulos D., Garcia C., Georgescu A.M.,
RA   Glavina T., Gomez M., Gonzales E., Groza M., Hammon N., Hawkins T.,
RA   Haydu L., Ho I., Huang W., Israni S., Jett J., Kadner K., Kimball H.,
RA   Kobayashi A., Larionov V., Leem S.-H., Lopez F., Lou Y., Lowry S.,
RA   Malfatti S., Martinez D., McCready P.M., Medina C., Morgan J.,
RA   Nelson K., Nolan M., Ovcharenko I., Pitluck S., Pollard M.,
RA   Popkie A.P., Predki P., Quan G., Ramirez L., Rash S., Retterer J.,
RA   Rodriguez A., Rogers S., Salamov A., Salazar A., She X., Smith D.,
RA   Slezak T., Solovyev V., Thayer N., Tice H., Tsai M., Ustaszewska A.,
RA   Vo N., Wagner M., Wheeler J., Wu K., Xie G., Yang J., Dubchak I.,
RA   Furey T.S., DeJong P., Dickson M., Gordon D., Eichler E.E.,
RA   Pennacchio L.A., Richardson P., Stubbs L., Rokhsar D.S., Myers R.M.,
RA   Rubin E.M., Lucas S.M.;
RT   "The DNA sequence and biology of human chromosome 19.";
RL   Nature 428:529-535(2004).
RN   [2] {ECO:0000313|Ensembl:ENSP00000471986}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
RN   [3] {ECO:0000313|Ensembl:ENSP00000491674}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (APR-2017) to UniProtKB.
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DR   EMBL; AC011476; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC245128; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_001138929.2; NM_001145457.2.
DR   UniGene; Hs.97084; -.
DR   ProteinModelPortal; A0A0A0MTU0; -.
DR   PRIDE; A0A0A0MTU0; -.
DR   Ensembl; ENST00000594765; ENSP00000471986; ENSG00000189430.
DR   Ensembl; ENST00000638385; ENSP00000491674; ENSG00000284113.
DR   Ensembl; ENST00000640312; ENSP00000492649; ENSG00000284208.
DR   GeneID; 9437; -.
DR   UCSC; uc061ctw.1; human.
DR   CTD; 9437; -.
DR   EuPathDB; HostDB:ENSG00000189430.12; -.
DR   HGNC; HGNC:6731; NCR1.
DR   OpenTargets; ENSG00000189430; -.
DR   eggNOG; ENOG410IX2G; Eukaryota.
DR   eggNOG; ENOG4111ACT; LUCA.
DR   GeneTree; ENSGT00940000153328; -.
DR   OrthoDB; 1327293at2759; -.
DR   ChiTaRS; NCR1; human.
DR   GenomeRNAi; 9437; -.
DR   Proteomes; UP000005640; Chromosome 19.
DR   Bgee; ENSG00000189430; Expressed in 73 organ(s), highest expression level in blood.
DR   ExpressionAtlas; A0A0A0MTU0; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 2.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   SMART; SM00409; IG; 2.
DR   SUPFAM; SSF48726; SSF48726; 2.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|MaxQB:A0A0A0MTU0,
KW   ECO:0000213|PeptideAtlas:A0A0A0MTU0};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    303       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014015972.
FT   TRANSMEM    255    273       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       34    115       IG. {ECO:0000259|SMART:SM00409}.
FT   DOMAIN      129    211       IG. {ECO:0000259|SMART:SM00409}.
SQ   SEQUENCE   303 AA;  34409 MW;  E34F5A817D81615B CRC64;
     MSSTLPALLC VGLCLSQRIS AQQQTLPKPF IWAEPHFMVP KEKQVTICCQ GNYGAVEYQL
     HFEGSLFAVD RPKPPERINK VQFYIPDMNS RMAGQYSCIY RVGELWSEPS NLLDLVVTEM
     YDTPTLSVHP GPEVISGEKV TFYCRLDTAT SMFLLLKEGR SSHVQRGYGK VQAEFPLGPV
     TTAHRGTYRC FGSYNNHAWS FPSEPVKLLV TGDIENTSLA PEDPTFPDTW GTYLLTTETG
     LQKDHALWDH TAQNLLRMGL AFLVLVALVW FLVEDWLSRK RTRERASRAS TWEGRRRLNT
     QTL
//