ID   A0A0A0MTJ8_HUMAN        Unreviewed;       413 AA.
AC   A0A0A0MTJ8;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-JAN-2019, entry version 29.
DE   SubName: Full=Cell adhesion molecule 1 {ECO:0000313|Ensembl:ENSP00000442387};
DE   Flags: Fragment;
GN   Name=CADM1 {ECO:0000313|Ensembl:ENSP00000442387};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000442387, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000442387, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16554811; DOI=10.1038/nature04632;
RA   Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K.,
RA   Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T.,
RA   Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G.,
RA   Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C.,
RA   Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A.,
RA   Hattori M., Rogers J., Lander E.S., Sakaki Y.;
RT   "Human chromosome 11 DNA sequence and analysis including novel gene
RT   identification.";
RL   Nature 440:497-500(2006).
RN   [2] {ECO:0000213|PubMed:21269460}
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=21269460; DOI=10.1186/1752-0509-5-17;
RA   Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P.,
RA   Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.;
RT   "Initial characterization of the human central proteome.";
RL   BMC Syst. Biol. 5:17-17(2011).
RN   [3] {ECO:0000313|Ensembl:ENSP00000442387}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
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DR   EMBL; AP000462; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP000465; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP003179; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AP005020; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KC877463; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF455527; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; KF511123; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A0A0MTJ8; -.
DR   jPOST; A0A0A0MTJ8; -.
DR   Ensembl; ENST00000545380; ENSP00000442387; ENSG00000182985.
DR   UCSC; uc058how.1; human.
DR   EuPathDB; HostDB:ENSG00000182985.16; -.
DR   HGNC; HGNC:5951; CADM1.
DR   OpenTargets; ENSG00000182985; -.
DR   GeneTree; ENSGT00940000156093; -.
DR   ChiTaRS; CADM1; human.
DR   Proteomes; UP000005640; Chromosome 11.
DR   Bgee; ENSG00000182985; Expressed in 247 organ(s), highest expression level in cerebellum.
DR   ExpressionAtlas; A0A0A0MTJ8; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.10; -; 3.
DR   InterPro; IPR013162; CD80_C2-set.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003599; Ig_sub.
DR   InterPro; IPR003598; Ig_sub2.
DR   InterPro; IPR013106; Ig_V-set.
DR   InterPro; IPR003585; Neurexin-like.
DR   Pfam; PF08205; C2-set_2; 1.
DR   Pfam; PF07686; V-set; 1.
DR   SMART; SM00294; 4.1m; 1.
DR   SMART; SM00409; IG; 3.
DR   SMART; SM00408; IGc2; 3.
DR   SUPFAM; SSF48726; SSF48726; 3.
DR   PROSITE; PS50835; IG_LIKE; 3.
PE   1: Evidence at protein level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Disulfide bond {ECO:0000256|SAAS:SAAS00504776};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Proteomics identification {ECO:0000213|EPD:A0A0A0MTJ8,
KW   ECO:0000213|MaxQB:A0A0A0MTJ8, ECO:0000213|PeptideAtlas:A0A0A0MTJ8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Repeat {ECO:0000256|SAAS:SAAS00289622};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     43       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        44    413       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001974512.
FT   TRANSMEM    346    366       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       39    138       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      143    237       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   DOMAIN      242    316       Ig-like. {ECO:0000259|PROSITE:PS50835}.
FT   NON_TER       1      1       {ECO:0000313|Ensembl:ENSP00000442387}.
SQ   SEQUENCE   413 AA;  45533 MW;  A809F2698DAE3C8B CRC64;
     XSVVLPSGSQ CAAAAAAAAP PGLRLRLLLL LFSAAALIPT GDGQNLFTKD VTVIEGEVAT
     ISCQVNKSDD SVIQLLNPNR QTIYFRDFRP LKDSRFQLLN FSSSELKVSL TNVSISDEGR
     YFCQLYTDPP QESYTTITVL VPPRNLMIDI QKDTAVEGEE IEVNCTAMAS KPATTIRWFK
     GNTELKGKSE VEEWSDMYTV TSQLMLKVHK EDDGVPVICQ VEHPAVTGNL QTQRYLEVQY
     KPQVHIQMTY PLQGLTREGD ALELTCEAIG KPQPVMVTWV RVDDEMPQHA VLSGPNLFIN
     NLNKTDNGTY RCEASNIVGK AHSDYMLYVY DSRAGEEGSI RAVDHAVIGG VVAVVVFAML
     CLLIILGRYF ARHKGTYFTH EAKGADDAAD ADTAIINAEG GQNNSEEKKE YFI
//