ID   A0A0A0MTI9_HUMAN        Unreviewed;       189 AA.
AC   A0A0A0MTI9;
DT   07-JAN-2015, integrated into UniProtKB/TrEMBL.
DT   07-JAN-2015, sequence version 1.
DT   16-JAN-2019, entry version 26.
DE   SubName: Full=Actin-related protein 3C {ECO:0000313|Ensembl:ENSP00000440990};
GN   Name=ACTR3C {ECO:0000313|Ensembl:ENSP00000440990};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|Ensembl:ENSP00000440990, ECO:0000313|Proteomes:UP000005640};
RN   [1] {ECO:0000313|Ensembl:ENSP00000440990, ECO:0000313|Proteomes:UP000005640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12853948; DOI=10.1038/nature01782;
RA   Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA   Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R.,
RA   Wylie K., Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H.,
RA   Sun H., Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A.,
RA   Vanbrunt A., Nguyen C., Du F., Lamar B., Courtney L., Kalicki J.,
RA   Ozersky P., Bielicki L., Scott K., Holmes A., Harkins R., Harris A.,
RA   Strong C.M., Hou S., Tomlinson C., Dauphin-Kohlberg S.,
RA   Kozlowicz-Reilly A., Leonard S., Rohlfing T., Rock S.M.,
RA   Tin-Wollam A.-M., Abbott A., Minx P., Maupin R., Strowmatt C.,
RA   Latreille P., Miller N., Johnson D., Murray J., Woessner J.P.,
RA   Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W., Spieth J.,
RA   Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E., Cook L.L.,
RA   Hickenbotham M.T., Eldred J., Williams D., Bedell J.A., Mardis E.R.,
RA   Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA   Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K.,
RA   Simms E., Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S.,
RA   Baertsch R.A., Brent M.R., Keibler E., Flicek P., Bork P., Suyama M.,
RA   Bailey J.A., Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R.,
RA   Eddy S.R., McPherson J.D., Olson M.V., Eichler E.E., Green E.D.,
RA   Waterston R.H., Wilson R.K.;
RT   "The DNA sequence of human chromosome 7.";
RL   Nature 424:157-164(2003).
RN   [2] {ECO:0000313|Ensembl:ENSP00000440990}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2014) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the actin family.
CC       {ECO:0000256|RuleBase:RU000487}.
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DR   EMBL; AC005586; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AC006008; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   ProteinModelPortal; A0A0A0MTI9; -.
DR   jPOST; A0A0A0MTI9; -.
DR   PeptideAtlas; A0A0A0MTI9; -.
DR   Ensembl; ENST00000539352; ENSP00000440990; ENSG00000106526.
DR   UCSC; uc064jcg.1; human.
DR   EuPathDB; HostDB:ENSG00000106526.10; -.
DR   HGNC; HGNC:37282; ACTR3C.
DR   OpenTargets; ENSG00000106526; -.
DR   eggNOG; KOG0678; Eukaryota.
DR   eggNOG; COG5277; LUCA.
DR   GeneTree; ENSGT00940000158304; -.
DR   ChiTaRS; ACTR3C; human.
DR   Proteomes; UP000005640; Chromosome 7.
DR   Bgee; ENSG00000106526; Expressed in 122 organ(s), highest expression level in right lobe of liver.
DR   ExpressionAtlas; A0A0A0MTI9; baseline and differential.
DR   GO; GO:0005885; C:Arp2/3 protein complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0034314; P:Arp2/3 complex-mediated actin nucleation; IEA:InterPro.
DR   InterPro; IPR004000; Actin.
DR   InterPro; IPR015623; Arp3.
DR   PANTHER; PTHR11937; PTHR11937; 1.
DR   PANTHER; PTHR11937:SF170; PTHR11937:SF170; 1.
DR   Pfam; PF00022; Actin; 1.
DR   SMART; SM00268; ACTIN; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000005640};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005640};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     21       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        22    189       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5001967324.
SQ   SEQUENCE   189 AA;  21313 MW;  5E31878D8A021873 CRC64;
     MFESFNVPGL YIAVQAVLAL AASWTSRQVG ERTLTGIVID SGDGVTHVIP VAEGYVIGSC
     IKHIPIAGRD ITYFIQQLLR EREVGIPPEQ SLETAKAIKE KYCYICPDIV KEFAKYDVDP
     QKWIKQYTGI NAINQKKFVI DVGYERFLGP EIFFHPEFAN PDSMESISDV VDEVIQNCPI
     DVRRPLYKV
//